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journalStr:"Journal of medicinal chemistry"
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PubPharm (17)
1
1-substituted (Dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-ones endowed with dual DNA-PK/PI3-K inhibitory activity
enthalten in:
Journal of medicinal chemistry
| 2013
von
Cano, C.
|
Saravanan, K.
|
Bailey, C.
| +14
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2
1-Substituted (Dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-ones Endowed with Dual DNA-PK/PI3-K Inhibitory Activity
enthalten in:
Journal of medicinal chemistry
| 2013
von
Cano, C.
|
Saravanan, K.
|
Bailey, C.
| +14
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3
Nucleoside transport inhibitors : structure-activity relationships for pyrimido[5,4-d]pyrimidine derivatives that potentiate pemetrexed cytotoxicity in the presence of α1-acid glycoprotein
enthalten in:
Journal of medicinal chemistry
| 2011
von
Saravanan, K.
|
Barlow, H.
|
Barton, M.
| +7
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4
Nucleoside Transport Inhibitors: Structure−Activity Relationships for Pyrimido[5,4-d]pyrimidine Derivatives That Potentiate Pemetrexed Cytotoxicity in the Presence of α1-Acid Glycoprotein
enthalten in:
Journal of medicinal chemistry
| 2011
von
Saravanan, K.
|
Barlow, H.
|
Barton, M.
| +7
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5
DNA-dependent protein kinase (DNA-PK) inhibitors. Synthesis and biological activity of quinolin-4-one and pyridopyrimidin-4-one surrogates for the chromen-4-one chemotype
enthalten in:
Journal of medicinal chemistry
| 2010
von
Cano, C.
|
Barbeau, O.
|
Bailey, C.
| +14
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6
Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase
enthalten in:
Journal of medicinal chemistry
| 2007
von
Hollick, J.
|
Rigoreau, L.
|
Cano-Soumillac, C.
| +16
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7
Discovery of potent chromen-4-one inhibitors of the DNA-dependent protein kinase (DNA-PK) using a small-molecule library approach
enthalten in:
Journal of medicinal chemistry
| 2005
von
Hardcastle, I.
|
Cockcroft, X.
|
Curtin, N.
| +8
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8
Design, synthesis, and evaluation of 3,4-dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-ones as inhibitors of poly(ADP-ribose) polymerase
enthalten in:
Journal of medicinal chemistry
| 2004
von
Tikhe, J.
|
Webber, S.
|
Hostomsky, Z.
| +17
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9
Resistance-modifying agents. 11.(1) Pyrimido[5,4-d]pyrimidine modulators of antitumor drug activity. Synthesis and structure-activity relationships for nucleoside transport inhibition and binding to alpha1-acid glycoprotein
enthalten in:
Journal of medicinal chemistry
| 2004
von
Curtin, N.
|
Barlow, H.
|
Bowman, K.
| +8
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10
N2-substituted O6-cyclohexylmethylguanine derivatives : potent inhibitors of cyclin-dependent kinases 1 and 2
enthalten in:
Journal of medicinal chemistry
| 2004
von
Hardcastle, I.
|
Arris, C.
|
Bentley, J.
| +15
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Zeitschrift: Journal of medicinal chemistry
Medienart
17
Aufsätze
14
Gedruckte Aufsätze
3
E-Artikel
3
E-Ressourcen
Zeitschriftentitel
Journal of medicinal chemistry
Thema
11
Journal Article
7
Antineoplastic Agents
5
EC 2.7.11.1
5
Research Support, Non-U.S. Gov't
4
DNA-Activated Protein Kinase
3
5Z93L87A1R
3
Enzyme Inhibitors
3
Guanine
3
Morpholines
3
Poly(ADP-ribose) Polymerase Inhibitors
2
6PLQ3CP4P3
2
7GR28W0FJI
2
7M7YKX2N15
2
8L70Q75FXE
2
Adenosine Triphosphate
2
Antimetabolites, Antineoplastic
2
Benzopyrans
2
CDC2 Protein Kinase
2
CDC2-CDC28 Kinases
2
CDK2 protein, human
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Erscheinungszeitraum
16
2000-
1
1900-1999
Erscheinungsjahr(e)
Von:
Bis:
Sprache
11
Englisch
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