Structure-Based Screening of Potential Triterpenoids for Anti-Viral Activity Against SARS-CoV-2 and Related Coronaviruses
Triterpenoids possess valuable medicinal properties ranging from anti-microbial to anti-cancer. Some of them were known for their activity against HIV, Ebola and Influenza viruses. In this study, 108 triterpenoids were screened for its potential usage as anti-viral drug against SARS-CoV-2, MERS and SARS coronaviruses, using molecular docking calculation against their main proteases (Mpro) and ADME based drug-likeliness parameters..
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Preprint| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
chemRxiv.org - (2021) vom: 18. Nov. Zur Gesamtaufnahme - year:2021 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
Jeyaraj, Vijaya sundar [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| doi: |
10.26434/chemrxiv.12746558 |
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