Changes in HIV Treatment Differentiated Care Utilization During the COVID-19 Pandemic in Zambia

Abstract Background Differentiated service delivery (DSD) models aim to lessen the burden of HIV treatment on patients and providers in part by reducing requirements for facility visits and extending dispensing intervals. With the advent of the COVID-19 pandemic, minimizing patient contact with healthcare facilities and other patients, while maintaining treatment continuity and avoiding loss to care, has become more urgent, resulting in efforts to increase DSD uptake. We assessed the extent to which DSD coverage and antiretroviral treatment (ART) dispensing intervals have changed during the COVID-19 pandemic in Zambia.Methods We used patient data from Zambia’s electronic medical record system (SmartCare) for 737 health facilities, representing about 3/4 of all ART patients nationally, to compare the numbers and proportional distributions of patients enrolled in DSD models in the six months before and six months after the first case of COVID-19 was diagnosed in Zambia in March 2020. Segmented linear regression was used to determine whether the introduction of COVID-19 into Zambia further accelerated the increase in DSD scale-up.Results Between September 2019 and August 2020, 181,317 patients aged 15+ (81,520 and 99,797 from September 1, 2019 to March 1, 2020 and from March 1 to August 31, 2020, respectively) enrolled in DSD models in Zambia. Overall participation in all DSD models increased over the study period, but uptake varied by model. The rate of acceleration increased in the second period for home ART delivery (152%), ≤2-month fast-track (143%), and 3-month MMD (139%). There were significant decelerations in the increase in enrolment for 4-6-month fast-track (−28%) and ‘other’ models (−19%).Conclusions Participation in DSD models for stable ART patients in Zambia increased after the advent of COVID-19, but dispensing intervals diminished. Eliminating obstacles to longer dispensing intervals, including those related to supply chain management, should be prioritized to achieve the expected benefits of DSD models and minimize COVID-19 risk..

Medienart:

Preprint

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

bioRxiv.org - (2022) vom: 22. Dez. Zur Gesamtaufnahme - year:2022

Sprache:

Englisch

Beteiligte Personen:

Jo, Youngji [VerfasserIn]
Rosen, Sydney [VerfasserIn]
Sy, Karla Therese L [VerfasserIn]
Phiri, Bevis [VerfasserIn]
Huber, Amy N [VerfasserIn]
Mwansa, Muya [VerfasserIn]
Shakwelele, Hilda [VerfasserIn]
Haimbe, Prudence [VerfasserIn]
Mwenechanya, Mpande M [VerfasserIn]
Mulenga, Priscilla Lumano [VerfasserIn]
Nichols, Brooke E [VerfasserIn]

Links:

Volltext [kostenfrei]

Themen:

570
Biology

doi:

10.1101/2021.03.20.21254021

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

XBI020201060