Survey of peridomestic mammal susceptibility to SARS-CoV-2 infection
Abstract Wild animals have been implicated as the origin of SARS-CoV-2, but it is largely unknown how the virus affects most wildlife species and if wildlife could ultimately serve as a reservoir for maintaining the virus outside the human population. Here we show that several common peridomestic species, including deer mice, bushy-tailed woodrats, and striped skunks, are susceptible to infection and can shed the virus in respiratory secretions. In contrast, we demonstrate that cottontail rabbits, fox squirrels, Wyoming ground squirrels, black-tailed prairie dogs, house mice, and racoons are not susceptible to SARS-CoV-2 infection. Our work expands upon the existing knowledge base of susceptible species and provides evidence that human-wildlife interactions could result in continued transmission of SARS-CoV-2..
Medienart: |
Preprint |
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Erscheinungsjahr: |
2021 |
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Erschienen: |
2021 |
Enthalten in: |
bioRxiv.org - (2021) vom: 20. Apr. Zur Gesamtaufnahme - year:2021 |
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Sprache: |
Englisch |
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Beteiligte Personen: |
Bosco-Lauth, Angela M. [VerfasserIn] |
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Links: |
Volltext [kostenfrei] |
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doi: |
10.1101/2021.01.21.427629 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
XBI019783027 |
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520 | |a Abstract Wild animals have been implicated as the origin of SARS-CoV-2, but it is largely unknown how the virus affects most wildlife species and if wildlife could ultimately serve as a reservoir for maintaining the virus outside the human population. Here we show that several common peridomestic species, including deer mice, bushy-tailed woodrats, and striped skunks, are susceptible to infection and can shed the virus in respiratory secretions. In contrast, we demonstrate that cottontail rabbits, fox squirrels, Wyoming ground squirrels, black-tailed prairie dogs, house mice, and racoons are not susceptible to SARS-CoV-2 infection. Our work expands upon the existing knowledge base of susceptible species and provides evidence that human-wildlife interactions could result in continued transmission of SARS-CoV-2. | ||
700 | 1 | |a Root, J. Jeffrey |e verfasserin |4 aut | |
700 | 1 | |a Porter, Stephanie M. |e verfasserin |4 aut | |
700 | 1 | |a Walker, Audrey E. |e verfasserin |4 aut | |
700 | 1 | |a Guilbert, Lauren |e verfasserin |4 aut | |
700 | 1 | |a Hawvermale, Daphne |e verfasserin |4 aut | |
700 | 1 | |a Pepper, Aimee |e verfasserin |4 aut | |
700 | 1 | |a Maison, Rachel M. |e verfasserin |4 aut | |
700 | 1 | |a Hartwig, Airn E. |e verfasserin |4 aut | |
700 | 1 | |a Gordy, Paul |e verfasserin |4 aut | |
700 | 1 | |a Bielefeldt-Ohmann, Helle |e verfasserin |4 aut | |
700 | 1 | |a Bowen, Richard A. |e verfasserin |4 aut | |
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