Short-term effectiveness of HIV care coordination among persons with recent HIV diagnosis or history of poor HIV outcomes

Abstract The New York City HIV Care Coordination Program (CCP) combines multiple evidence-based strategies to support persons living with HIV (PLWH) at risk for, or with a recent history of, poor HIV outcomes. We assessed the comparative effectiveness of the CCP by merging programmatic data on CCP clients with population-based surveillance data on all New York City PLWH. A non-CCP comparison group of similar PLWH who met CCP eligibility criteria was identified using surveillance data. The CCP and non-CCP groups were matched on propensity for CCP enrollment within four baseline treatment status groups (newly diagnosed or previously diagnosed and either consistently unsuppressed, inconsistently suppressed or consistently suppressed). We compared CCP to non-CCP proportions with viral load suppression at 12-month follow-up. Among the 13,624 persons included, 15·3% were newly diagnosed; among the 84·7% previously diagnosed, 14·2% were consistently suppressed, 28·9% were inconsistently suppressed, and 41 ·6% were consistently unsuppressed in the year prior to baseline. At 12-month follow-up, 59·9% of CCP and 53·9% of non-CCP participants had viral load suppression (Relative Risk=1.11, 95%CI:1.08-1.14). Among those newly diagnosed and those consistently unsuppressed at baseline, the relative risk of viral load suppression in the CCP versus non-CCP participants was 1.15 (95%CI:1.09-1.23) and 1.32 (95%CI:1.23-1.42), respectively. CCP exposure shows benefits over no CCP exposure for persons newly diagnosed or consistently unsuppressed, but not for persons suppressed in the year prior to baseline. We recommend more targeted case finding for CCP enrollment and increased attention to viral load suppression maintenance..

Medienart:

Preprint

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

bioRxiv.org - (2020) vom: 18. Jan. Zur Gesamtaufnahme - year:2020

Sprache:

Englisch

Beteiligte Personen:

Nash, Denis [VerfasserIn]
Robertson, McKaylee M. [VerfasserIn]
Penrose, Kate [VerfasserIn]
Chamberlin, Stephanie [VerfasserIn]
Robbins, Rebekkah S. [VerfasserIn]
Braunstein, Sarah L. [VerfasserIn]
Myers, Julie E. [VerfasserIn]
Abraham, Bisrat [VerfasserIn]
Kulkarni, Sarah [VerfasserIn]
Waldron, Levi [VerfasserIn]
Levin, Bruce [VerfasserIn]
Irvine, Mary K. [VerfasserIn]

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doi:

10.1101/311597

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

XBI000271756