One-step, Wash-free, Nanoparticle Clustering-based Magnetic Particle Spectroscopy (MPS) Bioassay Method for Detection of SARS-CoV-2 Spike and Nucleocapsid Proteins in Liquid Phase
With the ongoing global pandemic of coronavirus disease 2019 (COVID-19), there is an increasing quest for more accessible, easy-to-use, rapid, inexpensive, and high accuracy diagnostic tools. Traditional disease diagnostic methods such as qRT-PCR (quantitative reverse transcription-PCR) and ELISA (enzyme-linked immunosorbent assay) require multiple steps, trained technicians, and long turnaround time that may worsen the disease surveillance and pandemic control. In sight of this situation, a rapid, one-step, easy-to-use, and high accuracy diagnostic platform will be valuable for future epidemic control especially for regions with scarce medical resources. Herein, we report a magnetic particle spectroscopy (MPS) platform for detection of SARS-CoV-2 biomarkers: spike and nucleocapsid proteins..
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Preprint| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
arXiv.org - (2021) vom: 01. Aug. Zur Gesamtaufnahme - year:2021 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
Wu, Kai [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| PPN (Katalog-ID): |
XAR032326351 |
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| 100 | 1 | |a Wu, Kai |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a One-step, Wash-free, Nanoparticle Clustering-based Magnetic Particle Spectroscopy (MPS) Bioassay Method for Detection of SARS-CoV-2 Spike and Nucleocapsid Proteins in Liquid Phase |
| 264 | 1 | |c 2021 | |
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| 520 | |a With the ongoing global pandemic of coronavirus disease 2019 (COVID-19), there is an increasing quest for more accessible, easy-to-use, rapid, inexpensive, and high accuracy diagnostic tools. Traditional disease diagnostic methods such as qRT-PCR (quantitative reverse transcription-PCR) and ELISA (enzyme-linked immunosorbent assay) require multiple steps, trained technicians, and long turnaround time that may worsen the disease surveillance and pandemic control. In sight of this situation, a rapid, one-step, easy-to-use, and high accuracy diagnostic platform will be valuable for future epidemic control especially for regions with scarce medical resources. Herein, we report a magnetic particle spectroscopy (MPS) platform for detection of SARS-CoV-2 biomarkers: spike and nucleocapsid proteins. | ||
| 700 | 1 | |a Chugh, Vinit Kumar |e verfasserin |4 aut | |
| 700 | 1 | |a Krishna, Venkatramana D. |e verfasserin |4 aut | |
| 700 | 1 | |a di Girolamo, Arturo |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Yongqiang Andrew |e verfasserin |4 aut | |
| 700 | 1 | |a Saha, Renata |e verfasserin |4 aut | |
| 700 | 1 | |a Liang, Shuang |e verfasserin |4 aut | |
| 700 | 1 | |a Cheeran, Maxim C-J |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Jian-Ping |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t arXiv.org |g (2021) vom: 01. Aug. |
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| 856 | 4 | 0 | |u https://arxiv.org/abs/2108.01514 |z kostenfrei |3 Volltext |
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