Reported side-effects following Oxford/AstraZeneca COVID-19 vaccine in the north-west province, Iran : A cross-sectional study

Copyright: © 2024 Eterafi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited..

While the vaccination was introduced as a promising tool to control the Coronavirus disease 2019 (COVID-19) pandemic, concerns about vaccine-related side effects had grown. Due to the widespread administration of the COVID-19 vaccine worldwide for the first time, it was necessary to evaluate the safety and potential side effects in recipients. This study aims to assess, the incidence of adverse effects following Oxford-AstraZeneca vaccination and identify their related factors. In this cross-sectional survey-based study, 453 volunteers participated, including 235 men and 218 women. The reported adverse reactions from recipients of the ChAdOx1 nCoV-19 (Oxford-AstraZeneca) vaccine were collected by using a questionnaire. The findings showed that the incidence of adverse reactions, such as neurological, systematic, gastrointestinal, respiratory, and local symptoms were significantly higher after the first dose compared to the second dose. Systematic symptoms were the most prevalent reported side effects after the first and second dose injection. The demographical study of participants showed that individuals aged 18-34 and females were more prone to present adverse events following vaccination. However, no significant relationship was found between the occurrence of side effects and the recipients' body mass index. Despite the life-saving role of vaccination against SARS-CoV-2, it may have some adverse reactions in recipients. The severity and frequency of side effects were different. So, they were dependent on several factors, including gender and age. Altogether, post-vaccination adverse reactions were mild and tolerable.

Media Type:

Electronic Article

Year of Publication:

2024

Publication:

2024

Contained In:

To Main Record - volume:19

Contained In:

PloS one - 19(2024), 1 vom: 01., Seite e0296669

Language:

English

Contributors:

Eterafi, Majid [Author]
Fouladi, Nasrin [Author]
Golizadeh, Majid [Author]
Shaker, Hamidreza [Author]
Matin, Somaieh [Author]
Safarzadeh, Elham [Author]

Links:

Volltext

Keywords:

B5S3K2V0G8
ChAdOx1 nCoV-19
Journal Article

Notes:

Date Completed 08.01.2024

Date Revised 08.01.2024

published: Electronic-eCollection

Citation Status MEDLINE

doi:

10.1371/journal.pone.0296669

funding:

Supporting institution / Project title:

PPN (Catalogue-ID):

NLM366716409