Study Based on the Alliance Between Serum Magnesium Levels and Preterm Labor : An Inclusive Review

Copyright © 2023, Deeksha et al..

Preterm labor, regarded as the onset of labor before 37 weeks of gestation, is a highly prevalent issue in obstetrics with repercussions for neonatal health. This review article presents an in-depth analysis of the alliance between serum magnesium levels and preterm labor. The review explores the physiological roles of magnesium right through pregnancy, including its significance for energy metabolism, smooth muscle contraction, deoxyribonucleic acid (DNA), and protein synthesis. It addresses cellular transport and the homeostasis of magnesium. The pathophysiological processes encompassing inflammation, oxidative stress, calcium regulation, smooth muscle contractility, and neuroendocrine pathways are investigated. The review evaluates epidemiological studies investigating the alliance between serum magnesium levels and preterm labor. The review incorporates an assortment of study varieties, such as observational studies, case-control studies, prospective cohort studies, and meta-analyses. In the course of reviewing the prognostic relevance of serum magnesium levels in premature labor, therapeutic implications involving diagnostic precision, prognostic significance, and therapeutic response assessment have additionally been addressed. Therapeutic interventions targeting magnesium levels, such as magnesium supplementation, tocolytic therapy, and the role of magnesium in antenatal corticosteroid administration, are explored. This review provides an in-depth evaluation of the correlation between serum magnesium levels and preterm labor, stressing its therapeutic significance and repercussions for future research and treatment strategies.

Media Type:

Electronic Article

Year of Publication:

2023

Publication:

2023

Contained In:

To Main Record - volume:15

Contained In:

Cureus - 15(2023), 7 vom: 29. Juli, Seite e42602

Language:

English

Contributors:

Deeksha, H S [Author]
Pajai, Sandhya [Author]
Cherukuri, Srinidhi [Author]

Links:

Volltext

Keywords:

Alliance
Clinical implications
Epidemiology
Journal Article
Pathogenesis
Preterm labor
Review
Serum magnesium levels
Therapeutic interventions

Notes:

Date Revised 29.08.2023

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.7759/cureus.42602

funding:

Supporting institution / Project title:

PPN (Catalogue-ID):

NLM361397240