Brunner's gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding : A case report

©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved..

BACKGROUND: Brunner's gland hyperplasia (BGH) is a rare benign lesion of the duodenum. Lipomatous pseudohypertrophy (LiPH) of the pancreas is an extremely rare disease. Because each condition is rare, the probability of purely coincidental coexistence of both conditions is extremely low.

CASE SUMMARY: We report a 26-year-old man presenting to our hospital with symptoms of recurrent upper gastrointestinal bleeding. Upper gastrointestinal endoscopy showed a huge pedunculated polypoid lesion in the duodenum with bleeding at the base of the lesion. Histopathological examination of the duodenal biopsy specimens showed BGH. Besides, abdominal computed tomography and magnetic resonance imaging revealed marked fat replacement over the entire pancreas, confirmed by histopathological evaluation on percutaneous pancreatic biopsies. Based on the radiological and histological findings, LiPH of the pancreas and BGH were diagnosed. The patient refused any surgical intervention. Therefore, he was managed with supportive treatment. The patient's symptoms improved and there was no further bleeding.

CONCLUSION: This is the first well-documented case showing the coexistence of LiPH of the pancreas and BGH.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:9

Enthalten in:

World journal of clinical cases - 9(2021), 31 vom: 06. Nov., Seite 9670-9679

Sprache:

Englisch

Beteiligte Personen:

Nguyen, Long Cong [VerfasserIn]
Vu, Khanh Truong [VerfasserIn]
Vo, Trang Thi Thuy [VerfasserIn]
Trinh, Chau Ha [VerfasserIn]
Do, Tan Dang [VerfasserIn]
Pham, Ngoc Thi Van [VerfasserIn]
Pham, Tuyen Van [VerfasserIn]
Nguyen, Thanh Tuan [VerfasserIn]
Nguyen, Hiep Canh [VerfasserIn]
Byeon, Jeong-Sik [VerfasserIn]

Links:

Volltext

Themen:

Brunner’s gland
Case Reports
Case report
Gastrointestinal bleeding
Lipomatous pseudohypertrophy
Pancreas

Anmerkungen:

Date Revised 11.12.2021

published: Print

Citation Status PubMed-not-MEDLINE

doi:

10.12998/wjcc.v9.i31.9670

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM334139341