Two new organic acids from Portulaca oleracea L. and their anti-inflammatory and anticholinesterase activities
Two new organic acids, identified as (7E,9E,12E)-pentadecyl-7,9,12-trienoic acid, named Oleraceacid A (1), and 6,7-dihydroxy-4-(4-hydroxy-3,5-dimethoxyphenyl)-2-naphthoic acid, named Oleraceacid B (2), were isolated from Portulaca oleracea L.. The structures were verified by spectroscopic methods, including UHPLC-ESI-QTOF/MS, 1 D and 2 D NMR. Both Oleraceacid A (1) and Oleraceacid B (2) at 20 μM inhibited the inflammatory factor, IL-1β in the RAW 264.7 cells induced by LPS, moreover, Oleraceacid A (1) can inhibit cholinesterase activity.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:36 |
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| Enthalten in: |
Natural product research - 36(2022), 17 vom: 17. Sept., Seite 4401-4409 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Liu, Peishan [VerfasserIn] |
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| Links: |
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| Themen: |
Anti-Inflammatory Agents |
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| Anmerkungen: |
Date Completed 07.09.2022 Date Revised 07.09.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1080/14786419.2021.1999945 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM332875792 |
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| 520 | |a Two new organic acids, identified as (7E,9E,12E)-pentadecyl-7,9,12-trienoic acid, named Oleraceacid A (1), and 6,7-dihydroxy-4-(4-hydroxy-3,5-dimethoxyphenyl)-2-naphthoic acid, named Oleraceacid B (2), were isolated from Portulaca oleracea L.. The structures were verified by spectroscopic methods, including UHPLC-ESI-QTOF/MS, 1 D and 2 D NMR. Both Oleraceacid A (1) and Oleraceacid B (2) at 20 μM inhibited the inflammatory factor, IL-1β in the RAW 264.7 cells induced by LPS, moreover, Oleraceacid A (1) can inhibit cholinesterase activity | ||
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| 700 | 1 | |a Li, Huanfeng |e verfasserin |4 aut | |
| 700 | 1 | |a Tan, Lishuang |e verfasserin |4 aut | |
| 700 | 1 | |a Ying, Xixiang |e verfasserin |4 aut | |
| 700 | 1 | |a Ju, Baozhao |e verfasserin |4 aut | |
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