Assessment of the Risk of Breast Cancer Development Applying NCI Tool among Iraqi Women

OBJECTIVE: As part of the bioinformatics studies, we utilized National Cancer Institute (NCI)'s Breast Cancer Risk Assessment Tool to estimate the five-year period and lifetime risk of breast cancer development among Iraqi risky women.

METHODS: Totally, 110 risky women aged 21-67 (mean=36±7.4) years were interviewed by a series of questions regarding the risk of breast cancer development. Moreover, 100 cases with mutation in the BRCA1 or BRCA2 genes were included.

RESULTS: Our results demonstrated that the patient's estimated risk of breast cancer development during the next five years and lifetime (until the age 90 years) included 0.96% (p=0.211) and 9.97% (p=0.002), respectively being relatively low. Accordingly, the lifetime risk for the breast cancer development was significantly higher (10.38%) than that of 5-year. However, the age of patients was not significantly associated to the breast cancer development as there was no significant difference among various age groups.

CONCLUSION: It was concluded that long-term or lifetime period plays as a significant risk factor for developing breast cancer among female patients who had had a screening episode in Iraq.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:22

Enthalten in:

Asian Pacific journal of cancer prevention : APJCP - 22(2021), 10 vom: 01. Okt., Seite 3121-3126

Sprache:

Englisch

Beteiligte Personen:

Al Talebi, Zainab Abbas [VerfasserIn]
Ali, Seenaa Kadhum [VerfasserIn]
Kareem, Zinah Kadhim [VerfasserIn]
Al-Koofee, Dhafer A F [VerfasserIn]

Links:

Volltext

Themen:

Bioinformatics
Breast cancer
Journal Article
Risk Assessment Tool

Anmerkungen:

Date Completed 04.02.2022

Date Revised 05.04.2022

published: Electronic

Citation Status MEDLINE

doi:

10.31557/APJCP.2021.22.10.3121

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM332493075