suPAR, a Circulating Kidney Disease Factor
Copyright © 2021 Wei, Spear, Hahm and Reiser..
Urokinase plasminogen activator receptor (uPAR) is a multifaceted, GPI-anchored three-domain protein. Release of the receptor results in variable levels of soluble uPAR (suPAR) in the blood circulation. suPAR levels have been linked to many disease states. In this mini-review, we discuss suPAR as a key circulating molecule mediating kidney disease with a particular focus on differently spliced isoforms.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2021 |
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Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:8 |
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Enthalten in: |
Frontiers in medicine - 8(2021) vom: 03., Seite 745838 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Wei, Changli [VerfasserIn] |
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Links: |
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Themen: |
Isoform |
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Anmerkungen: |
Date Revised 26.10.2021 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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doi: |
10.3389/fmed.2021.745838 |
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funding: |
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PPN (Katalog-ID): |
NLM332328333 |
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