suPAR, a Circulating Kidney Disease Factor

Copyright © 2021 Wei, Spear, Hahm and Reiser..

Urokinase plasminogen activator receptor (uPAR) is a multifaceted, GPI-anchored three-domain protein. Release of the receptor results in variable levels of soluble uPAR (suPAR) in the blood circulation. suPAR levels have been linked to many disease states. In this mini-review, we discuss suPAR as a key circulating molecule mediating kidney disease with a particular focus on differently spliced isoforms.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:8

Enthalten in:

Frontiers in medicine - 8(2021) vom: 03., Seite 745838

Sprache:

Englisch

Beteiligte Personen:

Wei, Changli [VerfasserIn]
Spear, Ryan [VerfasserIn]
Hahm, Eunsil [VerfasserIn]
Reiser, Jochen [VerfasserIn]

Links:

Volltext

Themen:

Isoform
Journal Article
Kidney
Proteinuric disease
Review
SuPAR
UPAR

Anmerkungen:

Date Revised 26.10.2021

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.3389/fmed.2021.745838

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM332328333