Cognitive insights from tertiary sulci in prefrontal cortex
© 2021. The Author(s)..
The lateral prefrontal cortex (LPFC) is disproportionately expanded in humans compared to non-human primates, although the relationship between LPFC brain structures and uniquely human cognitive skills is largely unknown. Here, we test the relationship between variability in LPFC tertiary sulcal morphology and reasoning scores in a cohort of children and adolescents. Using a data-driven approach in independent discovery and replication samples, we show that the depth of specific LPFC tertiary sulci is associated with individual differences in reasoning scores beyond age. To expedite discoveries in future neuroanatomical-behavioral studies, we share tertiary sulcal definitions with the field. These findings support a classic but largely untested theory linking the protracted development of tertiary sulci to late-developing cognitive processes.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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| Enthalten in: |
Nature communications - 12(2021), 1 vom: 25. Aug., Seite 5122 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Voorhies, Willa I [VerfasserIn] |
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| Links: |
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| Themen: |
Journal Article |
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| Anmerkungen: |
Date Completed 24.09.2021 Date Revised 10.01.2024 published: Electronic Citation Status MEDLINE |
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| doi: |
10.1038/s41467-021-25162-w |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM329769642 |
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| 520 | |a © 2021. The Author(s). | ||
| 520 | |a The lateral prefrontal cortex (LPFC) is disproportionately expanded in humans compared to non-human primates, although the relationship between LPFC brain structures and uniquely human cognitive skills is largely unknown. Here, we test the relationship between variability in LPFC tertiary sulcal morphology and reasoning scores in a cohort of children and adolescents. Using a data-driven approach in independent discovery and replication samples, we show that the depth of specific LPFC tertiary sulci is associated with individual differences in reasoning scores beyond age. To expedite discoveries in future neuroanatomical-behavioral studies, we share tertiary sulcal definitions with the field. These findings support a classic but largely untested theory linking the protracted development of tertiary sulci to late-developing cognitive processes | ||
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| 700 | 1 | |a Bunge, Silvia A |e verfasserin |4 aut | |
| 700 | 1 | |a Weiner, Kevin S |e verfasserin |4 aut | |
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