Lupus anticoagulant and ischemic strokes : about two case reports
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by thrombotic clinical manifestations, including ischemic stroke. Testing for lupus anticoagulant (LA) among antiphospholipid antibodies is key to the diagnosis of antiphospholipid syndrome (APS). Given the impact on patient management, close clinician-pathologist collaboration is crucial for the presence of LA in a thrombotic setting. Testing for LA must be carried out using specific and appropriate clotting assays and the pathologist should be aware of interferences. We report here two cases of stroke associated with the presence of LA, and recall the strategy for screening for LA.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:79 |
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| Enthalten in: |
Annales de biologie clinique - 79(2021), 4 vom: 01. Aug., Seite 361-367 |
| Sprache: |
Französisch |
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| Weiterer Titel: |
Anticoagulant lupique et accidents vasculaires cérébraux ischémiques : à propos de deux observations |
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| Beteiligte Personen: |
Hilaire, Julie [VerfasserIn] |
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| Links: |
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| Themen: |
Antiphosholipid antibodies |
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| Anmerkungen: |
Date Completed 25.10.2021 Date Revised 25.10.2021 published: Print Citation Status MEDLINE |
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| doi: |
10.1684/abc.2021.1662 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM329708171 |
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| 520 | |a Antiphospholipid syndrome (APS) is an autoimmune disease characterized by thrombotic clinical manifestations, including ischemic stroke. Testing for lupus anticoagulant (LA) among antiphospholipid antibodies is key to the diagnosis of antiphospholipid syndrome (APS). Given the impact on patient management, close clinician-pathologist collaboration is crucial for the presence of LA in a thrombotic setting. Testing for LA must be carried out using specific and appropriate clotting assays and the pathologist should be aware of interferences. We report here two cases of stroke associated with the presence of LA, and recall the strategy for screening for LA | ||
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