A controlled human intervention trial to study protein quality by amino acid uptake kinetics with the novel Lemna protein concentrate as case study

A human intervention trial was conducted to study amino acid uptake of the novel Lemna protein concentrate (LPC) in comparison to whey (WPC). The study was a cross-over, double-blind, controlled trial in which 12 healthy participants received 20 grams of LPC and WPC in randomised order. The LPC consumption resulted in a significant lower postprandial increase in almost all individual amino acids, total amino acid (TAA) and total essential amino acids (TEAA) compared to WPC based on area under the curve (AUC) calculations. When the AUC after WPC consumption was set at 100%, LPC showed a relative AUC of 60.4% for TAA and 66.3% for the TEAA. Interindividual variation for LPC was high with an uptake of TEAA of LPC compared to WPC ranging from 18.2 to 94.2%. Human intervention trials can partly replace animal trials as they fully reflect the human situation and provide estimates on individual variations.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:73

Enthalten in:

International journal of food sciences and nutrition - 73(2022), 2 vom: 19. März, Seite 251-262

Sprache:

Englisch

Beteiligte Personen:

Mes, Jurriaan J [VerfasserIn]
Esser, Diederik [VerfasserIn]
Oosterink, Els [VerfasserIn]
van den Dool, Ronald T M [VerfasserIn]
Engel, Jasper [VerfasserIn]
de Jong, Govardus A H [VerfasserIn]
Wehrens, Ron [VerfasserIn]
van der Meer, Ingrid M [VerfasserIn]

Links:

Volltext

Themen:

3Rs
Amino Acids
Amino acid uptake
Duckweed
In vivo protein digestibility
Journal Article
Lemna
Protein concentrate
Randomized Controlled Trial
Whey Proteins

Anmerkungen:

Date Completed 16.02.2022

Date Revised 16.02.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1080/09637486.2021.1960958

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM329512455