A red-emissive two-photon fluorescent probe for mitochondrial sodium ions in live tissue
A cyclocyanine (CC)-based organic small molecule two-photon (TP) fluorescent probe (CCNa1) was developed for mitochondrial sodium ion sensing. CCNa1 exhibits a low solvatochromic shift and strong TP fluorescence enhancement at 575 nm upon binding to Na+ and is insensitive to other metal ions and to pH. CCNa1 demonstrated fast cell loading ability, biocompatibility, and sensitive response to mitochondrial Na+ influx in live cells and mouse brain tissue.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:57 |
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| Enthalten in: |
Chemical communications (Cambridge, England) - 57(2021), 71 vom: 06. Sept., Seite 8929-8932 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Juvekar, Vinayak [VerfasserIn] |
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| Links: |
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| Themen: |
9NEZ333N27 |
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| Anmerkungen: |
Date Completed 12.10.2021 Date Revised 12.10.2021 published: Electronic Citation Status MEDLINE |
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| doi: |
10.1039/d1cc03617c |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM329407635 |
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| 520 | |a A cyclocyanine (CC)-based organic small molecule two-photon (TP) fluorescent probe (CCNa1) was developed for mitochondrial sodium ion sensing. CCNa1 exhibits a low solvatochromic shift and strong TP fluorescence enhancement at 575 nm upon binding to Na+ and is insensitive to other metal ions and to pH. CCNa1 demonstrated fast cell loading ability, biocompatibility, and sensitive response to mitochondrial Na+ influx in live cells and mouse brain tissue | ||
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| 700 | 1 | |a Kang, Hyuk |e verfasserin |4 aut | |
| 700 | 1 | |a Song, Ju Man |e verfasserin |4 aut | |
| 700 | 1 | |a Je, Jong Tae |e verfasserin |4 aut | |
| 700 | 1 | |a Kim, Hwan Myung |e verfasserin |4 aut | |
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