High-Strength and Nonfouling Zwitterionic Triple-Network Hydrogel in Saline Environments
© 2021 Wiley-VCH GmbH..
Zwitterionic hydrogels have received great attention due to their excellent nonfouling and biocompatible properties, but they suffer from weak mechanical strength in the saline environments important for biomedical and engineering applications due to the "anti-polyelectrolyte" effect. Conventional strategies to introduce hydrophobic or non-zwitterionic components to increase mechanical strength compromise their nonfouling properties. Here, a highly effective strategy is reported to achieve both high mechanical strength and excellent nonfouling properties by constructing a pure zwitterionic triple-network (ZTN) hydrogel. The strong electrostatic interaction and network entanglement within the triple-network structure can effectively dissipate energy to toughen the hydrogel and achieve high strength, toughness, and stiffness in saline environments (compressive fracture stress 18.2 ± 1.4 MPa, toughness 1.62 ± 0.03 MJ m-3 , and modulus 0.66 ± 0.03 MPa in seawater environments). Moreover, the ZTN hydrogel is shown to strongly resist the attachment of proteins, bacteria, and cells. The results provide a fundamental understanding to guide the design of tough nonfouling zwitterionic hydrogels for a broad range of applications.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:33 |
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| Enthalten in: |
Advanced materials (Deerfield Beach, Fla.) - 33(2021), 39 vom: 10. Okt., Seite e2102479 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Li, Xiaohui [VerfasserIn] |
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| Links: |
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| Themen: |
High-strength materials |
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| Anmerkungen: |
Date Completed 04.10.2021 Date Revised 04.10.2021 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1002/adma.202102479 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM329311859 |
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| 520 | |a © 2021 Wiley-VCH GmbH. | ||
| 520 | |a Zwitterionic hydrogels have received great attention due to their excellent nonfouling and biocompatible properties, but they suffer from weak mechanical strength in the saline environments important for biomedical and engineering applications due to the "anti-polyelectrolyte" effect. Conventional strategies to introduce hydrophobic or non-zwitterionic components to increase mechanical strength compromise their nonfouling properties. Here, a highly effective strategy is reported to achieve both high mechanical strength and excellent nonfouling properties by constructing a pure zwitterionic triple-network (ZTN) hydrogel. The strong electrostatic interaction and network entanglement within the triple-network structure can effectively dissipate energy to toughen the hydrogel and achieve high strength, toughness, and stiffness in saline environments (compressive fracture stress 18.2 ± 1.4 MPa, toughness 1.62 ± 0.03 MJ m-3 , and modulus 0.66 ± 0.03 MPa in seawater environments). Moreover, the ZTN hydrogel is shown to strongly resist the attachment of proteins, bacteria, and cells. The results provide a fundamental understanding to guide the design of tough nonfouling zwitterionic hydrogels for a broad range of applications | ||
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| 650 | 4 | |a zwitterionic hydrogels | |
| 700 | 1 | |a Tang, Chenjue |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Di |e verfasserin |4 aut | |
| 700 | 1 | |a Yuan, Zhefan |e verfasserin |4 aut | |
| 700 | 1 | |a Hung, Hsiang-Chieh |e verfasserin |4 aut | |
| 700 | 1 | |a Luozhong, Sijin |e verfasserin |4 aut | |
| 700 | 1 | |a Gu, Wenchao |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Kan |e verfasserin |4 aut | |
| 700 | 1 | |a Jiang, Shaoyi |e verfasserin |4 aut | |
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