Beryllium in contaminated soils : Implication of beryllium bioaccessibility by different exposure pathways

Copyright © 2021 Elsevier B.V. All rights reserved..

Inhalation exposure and beryllium (Be) toxicity are well-known, but research on bioaccessibility from soils via different exposure pathways is limited. This study examined soils from a legacy radioactive waste disposal site using in vitro ingestion (Solubility Bioaccessibility Research Consortium [SBRC], physiologically based extraction test [PBET], in vitro gastrointestinal [IVG]), inhalation (simulated epithelial lung fluid [SELF]) and dynamic two-stage bioaccessibility (TBAc) methods, as well as 0.43 M HNO3 extraction. The results showed, 70 ± 4.8%, 56 ± 16.8% and 58 ± 5.7% of total Be were extracted (gastric phase [GP] + intestinal phase [IP]) in the SBRC, PBET, and IVG methods, respectively. Similar bioaccessibility of Be (~18%) in PBET-IP and SELF was due to chelating agents in the extractant. Moreover, TBAc-IP showed higher extraction (20.8 ± 2.0%) in comparison with the single-phase (SBRC-IP) result (4.8 ± 0.23%), suggesting increased Be bioaccessibility and toxicity in the gastrointestinal tract when the contamination derives from the inhalation route. The results suggested Be bioaccessibility depends on solution pH; time of extraction; soil reactive fractions (organic-inorganic); particle size, and the presence of chelating agents in the fluid. This study has significance for understanding Be bioaccessibility via different exposure routes and the application of risk-based management of Be-contaminated sites.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:421

Enthalten in:

Journal of hazardous materials - 421(2022) vom: 05. Jan., Seite 126757

Sprache:

Englisch

Beteiligte Personen:

Islam, Md Rashidul [VerfasserIn]
Sanderson, Peter [VerfasserIn]
Naidu, Ravi [VerfasserIn]
Payne, Timothy E [VerfasserIn]
Johansen, Mathew P [VerfasserIn]
Bari, A S M Fazle [VerfasserIn]
Rahman, Mohammad Mahmudur [VerfasserIn]

Links:

Volltext

Themen:

Arsenic
Beryllium
Bioaccessibility
Exposure route
In vitro assay
Journal Article
N712M78A8G
OW5102UV6N
Research Support, Non-U.S. Gov't
Soil
Soil Pollutants

Anmerkungen:

Date Completed 26.10.2021

Date Revised 26.10.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.jhazmat.2021.126757

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM328968323