The positive effects of surgery on symptomatic stereotactic radiation-induced peritumoral brain edema : A report of three cases
Copyright: © 2021 Surgical Neurology International..
BACKGROUND: Peritumoral brain edema is an uncommon but life-threatening side effect of brain tumors radiosurgery. Medical therapy usually alleviates symptoms until edema spontaneously disappears. However, when peritumoral brain edema endangers the patient's life or medical therapy fails to guarantee an acceptable quality of life, surgery might be considered.
CASE DESCRIPTION: Our report focuses on three patients who developed extensive peritumoral brain edema after radiosurgery. Two were affected by vestibular schwannomas and one by a skull-base meningioma. Peritumoral brain edema worsened despite maximal medical therapy in all cases; therefore, surgical removal of the radiated lesion was carried out. In the first patient, surgery was overdue and resulted in a fatal outcome. On the other hand, in the latter two cases surgery was quickly effective. In all three cases, an unmanageable brain swelling was not found at surgery.
CONCLUSION: Surgical removal of brain tumors previously treated with radiosurgery was safe and effective in resolving shortly peritumoral brain edema. This solution should be considered in patients who do not respond to medical therapy and before worsening of clinical conditions. Interestingly, the expected brain swelling was not confirmed intraoperatively. In our experience, this magnetic resonance finding should not be considered a criterion to delay surgery.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
|---|---|
| Enthalten in: |
Surgical neurology international - 12(2021) vom: 15., Seite 358 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Stefini, Roberto [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Brain swelling |
|---|
| Anmerkungen: |
Date Revised 25.04.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.25259/SNI_111_2021 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM32889950X |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM32889950X | ||
| 003 | DE-627 | ||
| 005 | 20231225203933.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.25259/SNI_111_2021 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1096.xml |
| 035 | |a (DE-627)NLM32889950X | ||
| 035 | |a (NLM)34345498 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Stefini, Roberto |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The positive effects of surgery on symptomatic stereotactic radiation-induced peritumoral brain edema |b A report of three cases |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 25.04.2022 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a Copyright: © 2021 Surgical Neurology International. | ||
| 520 | |a BACKGROUND: Peritumoral brain edema is an uncommon but life-threatening side effect of brain tumors radiosurgery. Medical therapy usually alleviates symptoms until edema spontaneously disappears. However, when peritumoral brain edema endangers the patient's life or medical therapy fails to guarantee an acceptable quality of life, surgery might be considered | ||
| 520 | |a CASE DESCRIPTION: Our report focuses on three patients who developed extensive peritumoral brain edema after radiosurgery. Two were affected by vestibular schwannomas and one by a skull-base meningioma. Peritumoral brain edema worsened despite maximal medical therapy in all cases; therefore, surgical removal of the radiated lesion was carried out. In the first patient, surgery was overdue and resulted in a fatal outcome. On the other hand, in the latter two cases surgery was quickly effective. In all three cases, an unmanageable brain swelling was not found at surgery | ||
| 520 | |a CONCLUSION: Surgical removal of brain tumors previously treated with radiosurgery was safe and effective in resolving shortly peritumoral brain edema. This solution should be considered in patients who do not respond to medical therapy and before worsening of clinical conditions. Interestingly, the expected brain swelling was not confirmed intraoperatively. In our experience, this magnetic resonance finding should not be considered a criterion to delay surgery | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Brain swelling | |
| 650 | 4 | |a Meningioma | |
| 650 | 4 | |a Peritumoral brain edema | |
| 650 | 4 | |a Radiosurgery | |
| 650 | 4 | |a Vestibular schwannoma | |
| 700 | 1 | |a Peron, Stefano |e verfasserin |4 aut | |
| 700 | 1 | |a Lacamera, Alessandro |e verfasserin |4 aut | |
| 700 | 1 | |a Cividini, Andrea |e verfasserin |4 aut | |
| 700 | 1 | |a Fiaschi, Pietro |e verfasserin |4 aut | |
| 700 | 1 | |a Sicuri, Giovanni Marco |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Surgical neurology international |d 2010 |g 12(2021) vom: 15., Seite 358 |w (DE-627)NLM199824223 |x 2229-5097 |7 nnns |
| 773 | 1 | 8 | |g volume:12 |g year:2021 |g day:15 |g pages:358 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.25259/SNI_111_2021 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 12 |j 2021 |b 15 |h 358 | ||