Multifocal motor neuropathy and visual pathway impairment : A case report
© 2021 International Federation of Clinical Neurophysiology. Published by Elsevier B.V..
BACKGROUND: Multifocal motor neuropathy (MMN) occasionally presents with cranial nerve involvement. However, no MMN cases with visual pathway impairment demonstrated by visual evoked potential (VEP) have been reported.
CASE REPORT: A 36-year-old man was admitted to our hospital with progressive muscular weakness. On admission, neurological findings revealed bilateral muscle weakness and atrophy of the distal upper limbs. The blood tests were positive for GM-1 ganglioside antibodies. Nerve conduction studies revealed bilateral conduction block in the median nerve. He was diagnosed with MMN. Intravenous immunoglobulin treatment improved muscle weakness and blurred vision, which was not a complaint when he was first seen. Moreover, VEP showed a post-treatment shortening of P100 latency. These treatment effects were consistently observed for 3.5 years.
SIGNIFICANCE: Our findings suggested that MMN could affect the visual pathway through autoimmune mechanisms.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:6 |
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| Enthalten in: |
Clinical neurophysiology practice - 6(2021) vom: 23., Seite 191-193 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kido, Keisuke [VerfasserIn] |
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| Links: |
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| Themen: |
Case Reports |
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| Anmerkungen: |
Date Revised 25.04.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1016/j.cnp.2021.05.003 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM328527971 |
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| 520 | |a © 2021 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. | ||
| 520 | |a BACKGROUND: Multifocal motor neuropathy (MMN) occasionally presents with cranial nerve involvement. However, no MMN cases with visual pathway impairment demonstrated by visual evoked potential (VEP) have been reported | ||
| 520 | |a CASE REPORT: A 36-year-old man was admitted to our hospital with progressive muscular weakness. On admission, neurological findings revealed bilateral muscle weakness and atrophy of the distal upper limbs. The blood tests were positive for GM-1 ganglioside antibodies. Nerve conduction studies revealed bilateral conduction block in the median nerve. He was diagnosed with MMN. Intravenous immunoglobulin treatment improved muscle weakness and blurred vision, which was not a complaint when he was first seen. Moreover, VEP showed a post-treatment shortening of P100 latency. These treatment effects were consistently observed for 3.5 years | ||
| 520 | |a SIGNIFICANCE: Our findings suggested that MMN could affect the visual pathway through autoimmune mechanisms | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Intravenous immunoglobulin | |
| 650 | 4 | |a Nerve conduction study | |
| 650 | 4 | |a Visual evoked potential | |
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| 700 | 1 | |a Inoue, Manabu |e verfasserin |4 aut | |
| 700 | 1 | |a Hamano, Toshiaki |e verfasserin |4 aut | |
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