UCell : Robust and scalable single-cell gene signature scoring
© 2021 The Author(s)..
UCell is an R package for evaluating gene signatures in single-cell datasets. UCell signature scores, based on the Mann-Whitney U statistic, are robust to dataset size and heterogeneity, and their calculation demands less computing time and memory than other available methods, enabling the processing of large datasets in a few minutes even on machines with limited computing power. UCell can be applied to any single-cell data matrix, and includes functions to directly interact with Seurat objects. The UCell package and documentation are available on GitHub at https://github.com/carmonalab/UCell.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:19 |
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| Enthalten in: |
Computational and structural biotechnology journal - 19(2021) vom: 01., Seite 3796-3798 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Andreatta, Massimo [VerfasserIn] |
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| Links: |
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| Themen: |
Cell type |
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| Anmerkungen: |
Date Revised 07.11.2023 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1016/j.csbj.2021.06.043 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM328308870 |
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| 520 | |a © 2021 The Author(s). | ||
| 520 | |a UCell is an R package for evaluating gene signatures in single-cell datasets. UCell signature scores, based on the Mann-Whitney U statistic, are robust to dataset size and heterogeneity, and their calculation demands less computing time and memory than other available methods, enabling the processing of large datasets in a few minutes even on machines with limited computing power. UCell can be applied to any single-cell data matrix, and includes functions to directly interact with Seurat objects. The UCell package and documentation are available on GitHub at https://github.com/carmonalab/UCell | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Cell type | |
| 650 | 4 | |a Gene set enrichment | |
| 650 | 4 | |a Gene signature | |
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| 700 | 1 | |a Carmona, Santiago J |e verfasserin |4 aut | |
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