Reduction in COVID-19 prevalence in healthcare workers in a university hospital in southern Brazil after the start of vaccination
Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved..
INTRODUCTION: The quick spread of SARS-CoV-2 led to the development of vaccines that are capable of reducing infection and the number of more severe COVID-19 cases.
AIM: To assess COVID-19 prevalence among healthcare workers (HCWs) after vaccination against SARS-CoV-2.
METHODS: This was a cross-sectional study on the prevalence of COVID-19 diagnosis among 7523 HCWs vaccinated against SARS-CoV-2 with CoronaVac and ChAdOx1 nCoV-19 in a university hospital, in southern Brazil, between January 18 and March 18, 2021.The variables evaluated were: sex, age, work area, role, source of infection, previous diagnosis of COVID-19, date of vaccine administration, type of vaccine, and need for hospitalization. The statistical analysis used Poisson regression and Fisher's exact test with SPSS software version 25, and a level of significance set at 5%.
RESULTS: 813 vaccinated HCWs showed symptoms suggestive of COVID-19, of whom 35.4% (288) had a detectable result after undergoing RT-PCR for SARS-CoV-2. There was a reduction of 62% in new cases of COVID-19 among HCWs in the institution 7 weeks after the start of vaccine rollout.
CONCLUSION: Our data suggest that the vaccines used by the institution reduced the number of COVID-19 cases among healthcare workers, demonstrating the effectiveness of the vaccines.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:109 |
|---|---|
| Enthalten in: |
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 109(2021) vom: 01. Aug., Seite 283-285 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Toniasso, Sheila de Castro Cardoso [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
B5S3K2V0G8 |
|---|
| Anmerkungen: |
Date Completed 31.08.2021 Date Revised 24.04.2023 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.ijid.2021.07.025 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM328166154 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM328166154 | ||
| 003 | DE-627 | ||
| 005 | 20231225202354.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.ijid.2021.07.025 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1093.xml |
| 035 | |a (DE-627)NLM328166154 | ||
| 035 | |a (NLM)34271203 | ||
| 035 | |a (PII)S1201-9712(21)00582-8 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Toniasso, Sheila de Castro Cardoso |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Reduction in COVID-19 prevalence in healthcare workers in a university hospital in southern Brazil after the start of vaccination |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 31.08.2021 | ||
| 500 | |a Date Revised 24.04.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved. | ||
| 520 | |a INTRODUCTION: The quick spread of SARS-CoV-2 led to the development of vaccines that are capable of reducing infection and the number of more severe COVID-19 cases | ||
| 520 | |a AIM: To assess COVID-19 prevalence among healthcare workers (HCWs) after vaccination against SARS-CoV-2 | ||
| 520 | |a METHODS: This was a cross-sectional study on the prevalence of COVID-19 diagnosis among 7523 HCWs vaccinated against SARS-CoV-2 with CoronaVac and ChAdOx1 nCoV-19 in a university hospital, in southern Brazil, between January 18 and March 18, 2021.The variables evaluated were: sex, age, work area, role, source of infection, previous diagnosis of COVID-19, date of vaccine administration, type of vaccine, and need for hospitalization. The statistical analysis used Poisson regression and Fisher's exact test with SPSS software version 25, and a level of significance set at 5% | ||
| 520 | |a RESULTS: 813 vaccinated HCWs showed symptoms suggestive of COVID-19, of whom 35.4% (288) had a detectable result after undergoing RT-PCR for SARS-CoV-2. There was a reduction of 62% in new cases of COVID-19 among HCWs in the institution 7 weeks after the start of vaccine rollout | ||
| 520 | |a CONCLUSION: Our data suggest that the vaccines used by the institution reduced the number of COVID-19 cases among healthcare workers, demonstrating the effectiveness of the vaccines | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a SARS-CoV-2 | |
| 650 | 4 | |a healthcare workers | |
| 650 | 4 | |a vaccine | |
| 650 | 7 | |a COVID-19 Vaccines |2 NLM | |
| 650 | 7 | |a ChAdOx1 nCoV-19 |2 NLM | |
| 650 | 7 | |a B5S3K2V0G8 |2 NLM | |
| 700 | 1 | |a Fernandes, Fernando Schmidt |e verfasserin |4 aut | |
| 700 | 1 | |a Joveleviths, Dvora |e verfasserin |4 aut | |
| 700 | 1 | |a Filho, Fábio Fernandes Dantas |e verfasserin |4 aut | |
| 700 | 1 | |a Takahasi, Anderson Yudi |e verfasserin |4 aut | |
| 700 | 1 | |a Baldin, Camila Pereira |e verfasserin |4 aut | |
| 700 | 1 | |a Pereira, Robson Martins |e verfasserin |4 aut | |
| 700 | 1 | |a da Silva, Luciana Pereira |e verfasserin |4 aut | |
| 700 | 1 | |a Brum, Maria Carlota Borba |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases |d 1998 |g 109(2021) vom: 01. Aug., Seite 283-285 |w (DE-627)NLM094730857 |x 1878-3511 |7 nnns |
| 773 | 1 | 8 | |g volume:109 |g year:2021 |g day:01 |g month:08 |g pages:283-285 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.ijid.2021.07.025 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 109 |j 2021 |b 01 |c 08 |h 283-285 | ||