Altered Mental Status : An Important but Overlooked Presenting Symptom of COVID-19 in Older Adults
Copyright © 2021 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved..
OBJECTIVES: To determine whether altered mental status (AMS) as a presenting symptom in older adults with COVID-19 is independently associated with adverse outcomes.
METHODS: A retrospective single center observational study of admitted patients (n = 421) age greater than 60 and a positive COVID-19 test. Outcomes included mortality, intubation, acute respiratory distress syndrome, acute kidney injury, and acute cardiac injury. Multivariate regression analysis was used to determine if presenting with AMS was associated with adverse outcomes.
RESULTS: There was an increased risk of mortality (RR 1.29, 95% CI 1.05-1.57), intubation (RR 1.52, 95% CI 1.09-2.12) and AKI (RR 1.42, 95% CI 1.13-1.78) in patients that presented with AMS.
CONCLUSIONS: During a global pandemic, prognostic indicators are vital to help guide the clinical course of patients, reduce healthcare cost, and preserve life. Our study suggests that AMS can play a major role in diagnostic algorithms in older adults with COVID-19.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:29 |
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| Enthalten in: |
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 29(2021), 11 vom: 17. Nov., Seite 1166-1170 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Oommen, Alvin [VerfasserIn] |
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| Links: |
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| Themen: |
AKI |
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| Anmerkungen: |
Date Completed 15.10.2021 Date Revised 15.10.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.jagp.2021.06.004 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM328026859 |
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| 500 | |a Date Completed 15.10.2021 | ||
| 500 | |a Date Revised 15.10.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2021 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved. | ||
| 520 | |a OBJECTIVES: To determine whether altered mental status (AMS) as a presenting symptom in older adults with COVID-19 is independently associated with adverse outcomes | ||
| 520 | |a METHODS: A retrospective single center observational study of admitted patients (n = 421) age greater than 60 and a positive COVID-19 test. Outcomes included mortality, intubation, acute respiratory distress syndrome, acute kidney injury, and acute cardiac injury. Multivariate regression analysis was used to determine if presenting with AMS was associated with adverse outcomes | ||
| 520 | |a RESULTS: There was an increased risk of mortality (RR 1.29, 95% CI 1.05-1.57), intubation (RR 1.52, 95% CI 1.09-2.12) and AKI (RR 1.42, 95% CI 1.13-1.78) in patients that presented with AMS | ||
| 520 | |a CONCLUSIONS: During a global pandemic, prognostic indicators are vital to help guide the clinical course of patients, reduce healthcare cost, and preserve life. Our study suggests that AMS can play a major role in diagnostic algorithms in older adults with COVID-19 | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Observational Study | |
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| 650 | 4 | |a AMS | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Geriatrics | |
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| 650 | 4 | |a pandemic | |
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| 700 | 1 | |a Parmar, Priyanka |e verfasserin |4 aut | |
| 700 | 1 | |a Rosengarten, Sabrina |e verfasserin |4 aut | |
| 700 | 1 | |a Wilson, Clara |e verfasserin |4 aut | |
| 700 | 1 | |a Maini, Rohan |e verfasserin |4 aut | |
| 700 | 1 | |a Kim, Julie Minjae |e verfasserin |4 aut | |
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| 700 | 1 | |a Daniel, Pia |e verfasserin |4 aut | |
| 700 | 1 | |a Brietman, Igal |e verfasserin |4 aut | |
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