Using cross-species vaccination approaches to counter emerging infectious diseases

© 2021. Springer Nature Limited..

Since the initial use of vaccination in the eighteenth century, our understanding of human and animal immunology has greatly advanced and a wide range of vaccine technologies and delivery systems have been developed. The COVID-19 pandemic response leveraged these innovations to enable rapid development of candidate vaccines within weeks of the viral genetic sequence being made available. The development of vaccines to tackle emerging infectious diseases is a priority for the World Health Organization and other global entities. More than 70% of emerging infectious diseases are acquired from animals, with some causing illness and death in both humans and the respective animal host. Yet the study of critical host-pathogen interactions and the underlying immune mechanisms to inform the development of vaccines for their control is traditionally done in medical and veterinary immunology 'silos'. In this Perspective, we highlight a 'One Health vaccinology' approach and discuss some key areas of synergy in human and veterinary vaccinology that could be exploited to accelerate the development of effective vaccines against these shared health threats.

Media Type:

Electronic Article

Year of Publication:

2021

Contained In:

Nature reviews. Immunology - Vol. 21, No. 12 (2021), p. 815-822

Language:

English

Contributors:

Warimwe, George M
Francis, Michael J
Bowden, Thomas A
Thumbi, Samuel M
Charleston, Bryan

Links:

Volltext

Keywords:

*Vaccination
Animals
COVID-19
Communicable Diseases, Emerging
Cross Reactions
Humans
Journal Article
Research Support, Non-U.S. Gov't
Review
SARS-CoV-2
Species Specificity
Vaccines
Viral Zoonoses

Notes:

Date Completed 14.12.2021

Date Revised 17.12.2021

published: Print-Electronic

Citation Status MEDLINE

Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Physical Description:

Online-Ressource

doi:

10.1038/s41577-021-00567-2

PMID:

34140665

PPN (Catalogue-ID):

NLM327998407