Factors associated with a latency < 7 days after preterm premature rupture of membranes between 22 and 32 weeks of gestation in singleton pregnancies
Copyright © 2021 Elsevier Masson SAS. All rights reserved..
OBJECTIVE: To identify factors at admission associated with a latency < 7 days after Preterm premature rupture of membranes (PPROM) between 22 and 32 weeks of gestation in singleton pregnancies.
MATERIAL AND METHODS: A retrospective comparative study of all women with singleton pregnancies admitted for PPROM to an academic tertiary center during the 5-year period of 2015-2019. Women who gave birth < 7 days and ≥ 7 day after PPROM were compared. We determined risk at admission associated with a latency < 7 days after PPROM by logistic regression and identified high-risk subgroups by classification and regression tree (CART) analysis.
RESULTS: Among 174 eligible births, 76 (44%) women gave birth < 7 days after PPROM and 98 (56%) later. The two groups had similar maternal baseline and obstetric characteristics. In multivariate analysis, the following variables reported at admission were independently associated with a latency < 7 days: painful uterine contractions (aOR 3.9, 95%CI 1.1-7.4), cervical length < 20 mm (aOR 2.4, 95%CI 1.2-4.8), and C reactive protein ≥ 10 mg/L (aOR 2.4, 95% CI 1.3-4.8). Women with painful uterine contractions and cervical length at admission < 20 mm were at highest risk of latency < 7 days (rate: 91%). Conversely, the women at lowest risk were those without uterine contractions, with a cervical length ≥ 20 mm, and C-reactive protein < 10 mg/L at admission (rate: 22%).
CONCLUSION: Our results may be helpful in determining criteria at admission for selecting women eligible for outpatient care after an initial hospitalization.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:50 |
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| Enthalten in: |
Journal of gynecology obstetrics and human reproduction - 50(2021), 10 vom: 01. Dez., Seite 102194 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Benedetti, Charlotte [VerfasserIn] |
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| Links: |
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| Themen: |
Journal Article |
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| Anmerkungen: |
Date Completed 30.12.2021 Date Revised 30.12.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.jogoh.2021.102194 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM327715049 |
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| 100 | 1 | |a Benedetti, Charlotte |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Factors associated with a latency < 7 days after preterm premature rupture of membranes between 22 and 32 weeks of gestation in singleton pregnancies |
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| 500 | |a Date Completed 30.12.2021 | ||
| 500 | |a Date Revised 30.12.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2021 Elsevier Masson SAS. All rights reserved. | ||
| 520 | |a OBJECTIVE: To identify factors at admission associated with a latency < 7 days after Preterm premature rupture of membranes (PPROM) between 22 and 32 weeks of gestation in singleton pregnancies | ||
| 520 | |a MATERIAL AND METHODS: A retrospective comparative study of all women with singleton pregnancies admitted for PPROM to an academic tertiary center during the 5-year period of 2015-2019. Women who gave birth < 7 days and ≥ 7 day after PPROM were compared. We determined risk at admission associated with a latency < 7 days after PPROM by logistic regression and identified high-risk subgroups by classification and regression tree (CART) analysis | ||
| 520 | |a RESULTS: Among 174 eligible births, 76 (44%) women gave birth < 7 days after PPROM and 98 (56%) later. The two groups had similar maternal baseline and obstetric characteristics. In multivariate analysis, the following variables reported at admission were independently associated with a latency < 7 days: painful uterine contractions (aOR 3.9, 95%CI 1.1-7.4), cervical length < 20 mm (aOR 2.4, 95%CI 1.2-4.8), and C reactive protein ≥ 10 mg/L (aOR 2.4, 95% CI 1.3-4.8). Women with painful uterine contractions and cervical length at admission < 20 mm were at highest risk of latency < 7 days (rate: 91%). Conversely, the women at lowest risk were those without uterine contractions, with a cervical length ≥ 20 mm, and C-reactive protein < 10 mg/L at admission (rate: 22%) | ||
| 520 | |a CONCLUSION: Our results may be helpful in determining criteria at admission for selecting women eligible for outpatient care after an initial hospitalization | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Latency | |
| 650 | 4 | |a Preterm delivery | |
| 650 | 4 | |a Preterm premature rupture of membranes | |
| 700 | 1 | |a Korb, Diane |e verfasserin |4 aut | |
| 700 | 1 | |a Rotureau, Julie |e verfasserin |4 aut | |
| 700 | 1 | |a Lepercq, Jacques |e verfasserin |4 aut | |
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