Contributing factors for the withdrawal from treatment in neonates with respiratory failure

OBJECTIVE: To investigate the factors contributing to the withdrawal from treatment in neonates with respiratory failure.

METHODS: The medical data of 2 525 neonates with respiratory failure were retrospectively studied, who were reported in 30 hospitals of Jiangsu Province from January to December, 2019. According to whether a complete treatment was given, they were divided into a complete treatment group with 2 162 neonates and a withdrawal group with 363 neonates. A multivariate logistic regression analysis was used to investigate the factors contributing to the withdrawal from treatment in neonates with respiratory failure.

RESULTS: The multivariate logistic regression analysis showed that small-for-gestational-age birth, congenital abnormality, gestational age < 28 weeks, living in the rural area or county-level city, and maternal age < 25 years were risk factors for the withdrawal from treatment in neonates with respiratory failure (P < 0.05), while a higher 5-minute Apgar score and cesarean section were protective factors (P < 0.05). Furthermore, 176 answers were obtained from 160 parents of the neonates who were willing to tell the reason for the withdrawal from treatment, among which severe sequelae (44.9%, 79/176) had the highest frequency, followed by uncontrollable disease condition (24.4%, 43/176), family financial difficulties (18.2%, 32/176), and dependence on mechanical ventilation (12.5%, 22/176).

CONCLUSIONS: Small-for-gestational-age birth, congenital abnormality, gestational age, living area, maternal age, Apgar score at birth, and method of birth are contributing factors for the withdrawal from treatment in neonates with respiratory failure. A poor prognosis and a low quality of life in future might be major immediate causes of withdrawal from treatment in neonates with respiratory failure, which needs to be confirmed by further studies.

Medienart:

Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:23

Enthalten in:

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 23(2021), 6 vom: 22. Juni, Seite 588-592

Sprache:

Chinesisch

Beteiligte Personen:

Hang, Fei-Fei [VerfasserIn]
Lu, Ke-Yu [VerfasserIn]
Wu, Xin-Ping [VerfasserIn]
Cheng, Rui [VerfasserIn]

Themen:

Journal Article

Anmerkungen:

Date Completed 17.06.2021

Date Revised 02.04.2024

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM326784411