Rare but potentially life-threatening - Multisystem inflammatory syndrome in adults - a case description

Multisystem inflammatory syndrome in adults, MIS-A, is a rare but severe post-covid-19 immunologic complication. The presentation is similar to Multisystem inflammatory syndrome in children, MIS-C. Both MIS-A/C are life-threatening immunologic syndromes characterized by hypotension, skin rashes, myocardial affection, coagulopathy and GI symptoms.  Here we describe a case of MIS-A in a 35-year-old previously healthy female who, five weeks after a mild covid-19 infection, presented with a life-threatening immunological reaction. The patient made a swift recovery upon treatment with immunoglobulins, corticosteroids and an interleukin-1 receptor antagonist. We want to highlight the importance of immunological derangements following covid-19 infections in adults. We also present a treatment suggestion for MIS-A based on the management routine for MIS-C, which has been developed from international discussions and collaborations by pediatric rheumatologists in Sweden and around the world.

Media Type:

Electronic Article

Year of Publication:

2021

Contained In:

Lakartidningen - Vol. 118 (2021)

Language:

Swedish

Other Title:

Hyperinflammation hos vuxna med covid-19 – ovanligt men allvarligt

Contributors:

Berntson, Lillemor
von Seth, Magnus
Bülow Anderberg, Sara
Åkerström, Tobias
Kurland, Siri

Keywords:

*COVID-19
Adult
Case Reports
Child
Female
Humans
Journal Article
SARS-CoV-2
Sweden
Syndrome
Systemic Inflammatory Response Syndrome

Notes:

Date Completed 19.05.2021

Date Revised 19.05.2021

published: Electronic

Citation Status MEDLINE

Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Physical Description:

Online-Ressource

PMID:

33999400

PPN (Catalogue-ID):

NLM326635580