Behavior of the electron spin resonance signals in X-ray irradiated human fingernails for the establishment of a dose reconstruction procedure

© The Author(s) 2021. Published by Oxford University Press on behalf of The Japanese Radiation Research Society and Japanese Society for Radiation Oncology. All rights reserved. For permissions, please e-mail: journals.permissionsoup.com..

The retrospective dosimetry that follows accidental X-ray exposure is becoming more significant for improving radiation diagnosis and treatment. We investigated the dosimetric properties of electron spin resonance (ESR) signals in X-ray irradiated fingernails under conditions that resemble realistic situations. We collected fingernails from 12 Japanese donors between the ages of 30 to 70. The sampled fingernails were utilized for X-ray irradiation, mechanical stimulation and background measurements. We also collected 10 toenails from one of the donors to evaluate their differences from fingernails. Additionally, we prepared 15 samples from two donors to compare the signals generated by γ-rays to those by X-rays. After observing the linear dose-response for both X- and γ-ray irradiated samples, we found that the sensitivity of the air-absorbed dose of γ-ray irradiated samples was identical to that of X-ray irradiated samples. The effect from secondary electrons seemed to be small in fingernails. The inter-individual variation in the sensitivity was no greater than the intra-individual variation. The signal intensities in each measurement fluctuated about the linear response curve, and the size of the fluctuation was dependent on the sample. The average fluctuation corresponded to 1.7 Gy, and the standard deviation was 1.3 Gy. The signal induced by X-rays could be erased by soaking the samples in water and subsequently drying them for four days, which allowed us to estimate the signal intensity prior to the exposure. These characteristics of the ESR signal induced by X-rays facilitate the development of a feasible protocol for fingernail dose reconstruction.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:62

Enthalten in:

Journal of radiation research - 62(2021), 5 vom: 13. Sept., Seite 812-824

Sprache:

Englisch

Beteiligte Personen:

Hirota, Seiko [VerfasserIn]
Gonzales, Chryzel Angelica B [VerfasserIn]
Yasuda, Hiroshi [VerfasserIn]

Links:

Volltext

Themen:

Comparative Study
Electron paramagnetic resonance (EPR)
Electron spin resonance (ESR)
Fingernail
Journal Article
Retrospective dosimetry
Toenail

Anmerkungen:

Date Completed 31.01.2022

Date Revised 31.01.2022

published: Print

Citation Status MEDLINE

doi:

10.1093/jrr/rrab027

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM326441808