The relationship between duration and quality of sleep and upper respiratory tract infections : a systematic review

© Crown copyright 2021..

BACKGROUND: Upper respiratory tract infections (URTIs) are common, mostly self-limiting, but result in inappropriate antibiotic prescriptions. Poor sleep is cited as a factor predisposing to URTIs, but the evidence is unclear.

OBJECTIVE: To systematically review whether sleep duration and quality influence the frequency and duration of URTIs.

METHODS: Three databases and bibliographies of included papers were searched for studies assessing associations between sleep duration or quality and URTIs. We performed dual title and abstract selection, discussed full-text exclusion decisions and completed 50% of data extraction in duplicate. The Newcastle-Ottawa Quality Assessment Scale assessed study quality and we estimated odds ratios (ORs) using random effects meta-analysis.

RESULTS: Searches identified 5146 papers. Eleven met inclusion criteria, with nine included in meta-analyses: four good, two fair and five poor for risk of bias. Compared to study defined 'normal' sleep duration, shorter sleep was associated with increased URTIs (OR: 1.30, 95% confidence interval [CI]: 1.19-1.42, I2: 11%, P < 0.001) and longer sleep was not significantly associated (OR: 1.11 95% CI: 0.99-1.23, I2: 0%, P = 0.070). Sensitivity analyses using a 7- to 9-hour baseline found that sleeping shorter than 7-9 hours was associated with increased URTIs (OR: 1.31, 95% CI: 1.22-1.41, I2: 0%, P < 0.001). Sleeping longer than 7-9 hours was non-significantly associated with increased URTIs (OR: 1.15, 95% CI: 1.00-1.33, I2: 0%, P = 0.050, respectively). We were unable to pool sleep quality studies. No studies reported on sleep duration and URTI severity or duration.

CONCLUSIONS: Reduced sleep, particularly shorter than 7-9 hours, is associated with increased URTIs. Strategies improving sleep should be explored to prevent URTIs.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:38

Enthalten in:

Family practice - 38(2021), 6 vom: 24. Nov., Seite 802-810

Sprache:

Englisch

Beteiligte Personen:

Robinson, Charlotte H [VerfasserIn]
Albury, Charlotte [VerfasserIn]
McCartney, David [VerfasserIn]
Fletcher, Benjamin [VerfasserIn]
Roberts, Nia [VerfasserIn]
Jury, Imogen [VerfasserIn]
Lee, Joseph [VerfasserIn]

Links:

Volltext

Themen:

Anti-Bacterial Agents
Journal Article
Meta-Analysis
Prevention
Research Support, Non-U.S. Gov't
Sleep duration
Sleep quality
Systematic Review
Systematic review
URTI
Upper respiratory tract infection

Anmerkungen:

Date Completed 26.01.2022

Date Revised 26.01.2022

published: Print

Citation Status MEDLINE

doi:

10.1093/fampra/cmab033

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM32549178X