Implication of the New AJCC pT Classification of SCC of the Lip Comparing With Other Oral Subsites

© 2021 The American Laryngological, Rhinological and Otological Society, Inc..

OBJECTIVE: To determine the implication of the new AJCC staging system for pT classification in a cohort of patients with SCC of the lip mucosa and compare it to other oral cavity sites.

METHODS: Retrospective cohort of 744 patients treated between 2002 and 2017, by the Head and Neck Surgery Department of the University of Sao Paulo.

RESULTS: Of 95 lip patients, 42 had pT upstage (58.1% of pT1 to pT2-3 and 50% of pT2 to pT3). Similar DFS/OS observed for those pT1 maintained or upstaged to pT2-3, pT2 patients upstaged to pT3 presented worse OS (49.4% versus 92.3%, P = .032). The comparison between lip and other mouth topographies, denoted better prognosis for pT1-2, but not for pT3-4a. Lip tumors had lower DOI, rates of perineural/angiolymphatic invasion, nodal metastasis, recurrence, and death.

CONCLUSION: The inclusion of DOI to the new pT classification better stratifies patients with SCC of the lip mucosa upstaged to pT3 by assessing inferior OS.

LEVEL OF EVIDENCE: 3 Laryngoscope, 131:E2770-E2776, 2021.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:131

Enthalten in:

The Laryngoscope - 131(2021), 11 vom: 05. Nov., Seite E2770-E2776

Sprache:

Englisch

Beteiligte Personen:

Toledo, Loic Monginet [VerfasserIn]
de Oliveira, Adriana Santos [VerfasserIn]
Pinheiro, Renan Aguera [VerfasserIn]
Leite, Ana Kober Nogueira [VerfasserIn]
de Mello, Evandro Sobroza [VerfasserIn]
Moyses, Raquel Ajub [VerfasserIn]
Kulcsar, Marco Aurelio V [VerfasserIn]
Dedivitis, Rogério Aparecido [VerfasserIn]
Kowalski, Luiz Paulo [VerfasserIn]
Matos, Leandro Luongo [VerfasserIn]

Links:

Volltext

Themen:

Comparative Study
Journal Article
Lip
Neoplasm staging
Oral cavity neoplasms
Recurrence
Research Support, Non-U.S. Gov't
Survival

Anmerkungen:

Date Completed 22.11.2021

Date Revised 22.11.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1002/lary.29596

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM325025789