Implication of the New AJCC pT Classification of SCC of the Lip Comparing With Other Oral Subsites
© 2021 The American Laryngological, Rhinological and Otological Society, Inc..
OBJECTIVE: To determine the implication of the new AJCC staging system for pT classification in a cohort of patients with SCC of the lip mucosa and compare it to other oral cavity sites.
METHODS: Retrospective cohort of 744 patients treated between 2002 and 2017, by the Head and Neck Surgery Department of the University of Sao Paulo.
RESULTS: Of 95 lip patients, 42 had pT upstage (58.1% of pT1 to pT2-3 and 50% of pT2 to pT3). Similar DFS/OS observed for those pT1 maintained or upstaged to pT2-3, pT2 patients upstaged to pT3 presented worse OS (49.4% versus 92.3%, P = .032). The comparison between lip and other mouth topographies, denoted better prognosis for pT1-2, but not for pT3-4a. Lip tumors had lower DOI, rates of perineural/angiolymphatic invasion, nodal metastasis, recurrence, and death.
CONCLUSION: The inclusion of DOI to the new pT classification better stratifies patients with SCC of the lip mucosa upstaged to pT3 by assessing inferior OS.
LEVEL OF EVIDENCE: 3 Laryngoscope, 131:E2770-E2776, 2021.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2021 |
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Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:131 |
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Enthalten in: |
The Laryngoscope - 131(2021), 11 vom: 05. Nov., Seite E2770-E2776 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Toledo, Loic Monginet [VerfasserIn] |
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Links: |
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Themen: |
Comparative Study |
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Anmerkungen: |
Date Completed 22.11.2021 Date Revised 22.11.2021 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1002/lary.29596 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM325025789 |
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520 | |a © 2021 The American Laryngological, Rhinological and Otological Society, Inc. | ||
520 | |a OBJECTIVE: To determine the implication of the new AJCC staging system for pT classification in a cohort of patients with SCC of the lip mucosa and compare it to other oral cavity sites | ||
520 | |a METHODS: Retrospective cohort of 744 patients treated between 2002 and 2017, by the Head and Neck Surgery Department of the University of Sao Paulo | ||
520 | |a RESULTS: Of 95 lip patients, 42 had pT upstage (58.1% of pT1 to pT2-3 and 50% of pT2 to pT3). Similar DFS/OS observed for those pT1 maintained or upstaged to pT2-3, pT2 patients upstaged to pT3 presented worse OS (49.4% versus 92.3%, P = .032). The comparison between lip and other mouth topographies, denoted better prognosis for pT1-2, but not for pT3-4a. Lip tumors had lower DOI, rates of perineural/angiolymphatic invasion, nodal metastasis, recurrence, and death | ||
520 | |a CONCLUSION: The inclusion of DOI to the new pT classification better stratifies patients with SCC of the lip mucosa upstaged to pT3 by assessing inferior OS | ||
520 | |a LEVEL OF EVIDENCE: 3 Laryngoscope, 131:E2770-E2776, 2021 | ||
650 | 4 | |a Comparative Study | |
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650 | 4 | |a oral cavity neoplasms | |
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700 | 1 | |a Pinheiro, Renan Aguera |e verfasserin |4 aut | |
700 | 1 | |a Leite, Ana Kober Nogueira |e verfasserin |4 aut | |
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700 | 1 | |a Kowalski, Luiz Paulo |e verfasserin |4 aut | |
700 | 1 | |a Matos, Leandro Luongo |e verfasserin |4 aut | |
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