Predictive Factors for Restenosis Following Stent-Supported Endovascular Therapy with Intravascular Ultrasound Evaluation for Femoropopliteal Chronic Total Occlusion

Copyright © 2020 SIR. Published by Elsevier Inc. All rights reserved..

PURPOSE: To determine the predictive factors for in-stent restenosis (ISR) following stent-supported endovascular therapy (EVT) with intravascular ultrasound (US) evaluation for femoropopliteal chronic total occlusion.

MATERIALS AND METHODS: This was a single-center, retrospective, observational study. The study included 276 lesions in 251 patients who underwent stent-supported EVT with intravascular ultrasound evaluation for femoropopliteal chronic total occlusion from July 2012 to June 2019. The wire passage route was assessed using intravascular US, and lesions were classified accordingly into 2 groups: intraluminal and subintimal passage. In this study, the intraluminal group was further divided into 3 subgroups by severity of calcification: none, <180°, and ≥180° circumferential. The subintimal group was further divided into 2 subgroups: subintimal passage without or with calcification. The primary outcome measure was ISR. Cox proportional hazards regression was used to determine the association of clinical characteristics with ISR rates.

RESULTS: The mean follow-up period was 19 months ±16, during which time ISR was observed in 31% of lesions. After multivariate analysis, an increased degree of plaque burden (hazard ratio [HR] = 1.101) and subintimal passage with calcification (HR = 3.408) were associated with an increased risk of ISR; a larger distal external elastic membrane area (HR = 0.898) and use of a stent graft (HR = 0.130) were significantly associated with a reduced risk of ISR.

CONCLUSIONS: This study revealed that factors associated with ISR after stent-supported EVT with intravascular US evaluation were distal external elastic membrane area, plaque burden, subintimal passage with calcification, and use of a stent graft.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:32

Enthalten in:

Journal of vascular and interventional radiology : JVIR - 32(2021), 5 vom: 01. Mai, Seite 712-720.e1

Sprache:

Englisch

Beteiligte Personen:

Kurata, Naoya [VerfasserIn]
Iida, Osamu [VerfasserIn]
Takahara, Mitusyoshi [VerfasserIn]
Asai, Mitsutoshi [VerfasserIn]
Masuda, Masaharu [VerfasserIn]
Okamoto, Shin [VerfasserIn]
Ishihara, Takayuki [VerfasserIn]
Nanto, Kiyonori [VerfasserIn]
Mano, Toshiaki [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Observational Study

Anmerkungen:

Date Completed 16.08.2021

Date Revised 16.08.2021

published: Print

Citation Status MEDLINE

doi:

10.1016/j.jvir.2020.11.020

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM324863667