Inflammatory pseudotumor and myofibroblastic inflammatory tumor. Diagnostic criteria and prognostic differences
Copyright © 2021 AEC. Publicado por Elsevier España, S.L.U. All rights reserved..
INTRODUCTION: Inflammatory pseudotumor (IPT) and inflammatory myofibroblastic tumor (IMT) are two very rare entities that were formerly included in the same category; however, today they are considered two different diseases due to the neoplastic origin of the IMT. Our objective is to share our experience in the management of these two types of tumors that we must take into account in the differential diagnosis of pulmonary masses or nodules.
METHODS: Thirteen patients with a pathological diagnosis of IPT and IMT who underwent surgery between 2008 and 2019 were retrospectively studied. We recorded the pre and postoperative information of each one, as well as the survival analysis.
RESULTS: Of the 13 patients, 8 were men and 5 women. The mean age of presentation was 53,5 years. An atypical segmentectomy was performed in 6 patients; a lobectomy was necessary in 6 and a pneumonectomy in 1 case. In all cases a complete resection was achieved. Diagnosis was possible thanks to histology, immunohistochemical (IHQ) and fluorescent in situ hybridization (FISH) techniques determining the expression of IgG4 and the rearrangement of ALK, respectively. After a median follow up of 49 months, we didńt find any loco-regional or distant recurrence in the patients studied.
CONCLUSION: IPT and IMT are rare tumors with a very good prognostic. The diagnosis of both entities is based mainly on specific anatomopathological techniques. Surgery has, in most cases, both a diagnostic and therapeutic role.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2021 |
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| Enthalten in: |
Cirugia espanola - (2021) vom: 22. Apr. |
| Sprache: |
Englisch |
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| Weiterer Titel: |
Seudotumor inflamatorio y tumor miofibroblástico inflamatorio. Criterios diagnósticos y diferencias pronósticas |
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| Beteiligte Personen: |
Carrasco Rodríguez, Rommel [VerfasserIn] |
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| Links: |
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| Themen: |
Cirugía |
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| Anmerkungen: |
Date Revised 22.02.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1016/j.ciresp.2021.03.009 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM32450165X |
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| 100 | 1 | |a Carrasco Rodríguez, Rommel |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Inflammatory pseudotumor and myofibroblastic inflammatory tumor. Diagnostic criteria and prognostic differences |
| 246 | 3 | 3 | |a Seudotumor inflamatorio y tumor miofibroblástico inflamatorio. Criterios diagnósticos y diferencias pronósticas |
| 264 | 1 | |c 2021 | |
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| 500 | |a Date Revised 22.02.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a Copyright © 2021 AEC. Publicado por Elsevier España, S.L.U. All rights reserved. | ||
| 520 | |a INTRODUCTION: Inflammatory pseudotumor (IPT) and inflammatory myofibroblastic tumor (IMT) are two very rare entities that were formerly included in the same category; however, today they are considered two different diseases due to the neoplastic origin of the IMT. Our objective is to share our experience in the management of these two types of tumors that we must take into account in the differential diagnosis of pulmonary masses or nodules | ||
| 520 | |a METHODS: Thirteen patients with a pathological diagnosis of IPT and IMT who underwent surgery between 2008 and 2019 were retrospectively studied. We recorded the pre and postoperative information of each one, as well as the survival analysis | ||
| 520 | |a RESULTS: Of the 13 patients, 8 were men and 5 women. The mean age of presentation was 53,5 years. An atypical segmentectomy was performed in 6 patients; a lobectomy was necessary in 6 and a pneumonectomy in 1 case. In all cases a complete resection was achieved. Diagnosis was possible thanks to histology, immunohistochemical (IHQ) and fluorescent in situ hybridization (FISH) techniques determining the expression of IgG4 and the rearrangement of ALK, respectively. After a median follow up of 49 months, we didńt find any loco-regional or distant recurrence in the patients studied | ||
| 520 | |a CONCLUSION: IPT and IMT are rare tumors with a very good prognostic. The diagnosis of both entities is based mainly on specific anatomopathological techniques. Surgery has, in most cases, both a diagnostic and therapeutic role | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Cirugía | |
| 650 | 4 | |a Inflammatory myofibroblastic tumor | |
| 650 | 4 | |a Inflammatory pseudotumor | |
| 650 | 4 | |a Seudotumor inflamatorio | |
| 650 | 4 | |a Surgery | |
| 650 | 4 | |a Tumor miofibroblástico inflamatorio | |
| 700 | 1 | |a García Fontán, Eva María |e verfasserin |4 aut | |
| 700 | 1 | |a Blanco Ramos, Montserrat |e verfasserin |4 aut | |
| 700 | 1 | |a Juaneda Magdalena Benavides, Laura |e verfasserin |4 aut | |
| 700 | 1 | |a Otero Lozano, Daniel |e verfasserin |4 aut | |
| 700 | 1 | |a Moldes Rodriguez, Milagros |e verfasserin |4 aut | |
| 700 | 1 | |a Cañizares Carretero, Miguel Angel |e verfasserin |4 aut | |
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