Cervical cancer prevention among older women - challenges in screening, diagnostic workup and treatment

© 2021 Nordic Federation of Societies of Obstetrics and Gynecology (NFOG). Published by John Wiley & Sons Ltd..

Cervical cancer incidence and mortality have declined dramatically after screening for cervical cancer was implemented. Yet, studies have reported high cervical cancer incidence and mortality rates at older age despite low HPV prevalence and incidence of precursor lesions. The underlying reason for these findings remains unclear. However, it is well known that the impact of screening depends not only on the uptake and effectiveness of screening but also on the uptake and effectiveness of diagnostic workup (ie colposcopy), treatment and follow-up. In older women, sensitivity of screening and performance of colposcopy are impaired due to age-dependent changes to the cervix. In this commentary, we aimed to discuss challenges in screening and clinical management of older women, and to identify crucial areas of particular interest for future research.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:100

Enthalten in:

Acta obstetricia et gynecologica Scandinavica - 100(2021), 8 vom: 18. Aug., Seite 1364-1368

Sprache:

Englisch

Beteiligte Personen:

Gustafson, Line W [VerfasserIn]
Petersen, Lone Kjeld [VerfasserIn]
Bor, Pinar [VerfasserIn]
Andersen, Berit [VerfasserIn]
Hammer, Anne [VerfasserIn]

Links:

Volltext

Themen:

Cervical cancer screening
Cervical intraepithelial neoplasia
Colposcopy
High-risk HPV
Human papillomavirus
Journal Article
Postmenopausal
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 30.08.2021

Date Revised 07.12.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1111/aogs.14162

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM324212208