Hypoalbuminaemia in orthopaedic trauma patients in a rural hospital in South Africa
© 2021. SICOT aisbl..
BACKGROUND: The deleterious effects of hypoalbuminaemia in the peri-operative period are well documented. We aimed to review serum albumin levels in a cohort of orthopaedic trauma patients to determine the prevalence of hypoalbuminaemia. Secondarily, we aimed to identify factors associated with an increased risk of hypoalbuminaemia.
METHODS: A retrospective cross-sectional study was performed of data collected prospectively at a regional hospital serving primarily a rural population in South Africa.
RESULTS: Two hundred ninety-five patients were included in the study. Twenty-nine per cent of the cohort was found to have hypoalbuminaemia. Femur neck fractures (p < 0.001), intertrochanteric fractures (p = 0.004), tibial plateau fractures (p = 0.034) and polytrauma (p = 0.013) were associated with hypoalbuminaemia. The mean albumin level was lower in HIV-positive patients when compared to HIV-negative patients (35.7 g/L vs 37.5 g/L, p = 0.007). The presence of comorbidities other than HIV, like diabetes mellitus (p = 0.001), previous pulmonary tuberculosis (p = 0.034) and chronic renal failure (p = 0.007) was associated with hypoalbuminaemia.
CONCLUSION: In this cohort of orthopaedic trauma patients from rural South Africa, we found a 29% prevalence of hypoalbuminaemia at the time of presentation. High-risk subgroups include patients with pre-existing comorbidities and increased age, as well as patients presenting with polytrauma, femoral neck, intertrochanteric femur or tibial plateau fractures.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:46 |
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| Enthalten in: |
International orthopaedics - 46(2022), 1 vom: 01. Jan., Seite 37-42 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Maimin, D G [VerfasserIn] |
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| Links: |
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| Themen: |
Albumin |
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| Anmerkungen: |
Date Completed 09.03.2022 Date Revised 09.03.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s00264-021-05022-4 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM323894151 |
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| 500 | |a Date Revised 09.03.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2021. SICOT aisbl. | ||
| 520 | |a BACKGROUND: The deleterious effects of hypoalbuminaemia in the peri-operative period are well documented. We aimed to review serum albumin levels in a cohort of orthopaedic trauma patients to determine the prevalence of hypoalbuminaemia. Secondarily, we aimed to identify factors associated with an increased risk of hypoalbuminaemia | ||
| 520 | |a METHODS: A retrospective cross-sectional study was performed of data collected prospectively at a regional hospital serving primarily a rural population in South Africa | ||
| 520 | |a RESULTS: Two hundred ninety-five patients were included in the study. Twenty-nine per cent of the cohort was found to have hypoalbuminaemia. Femur neck fractures (p < 0.001), intertrochanteric fractures (p = 0.004), tibial plateau fractures (p = 0.034) and polytrauma (p = 0.013) were associated with hypoalbuminaemia. The mean albumin level was lower in HIV-positive patients when compared to HIV-negative patients (35.7 g/L vs 37.5 g/L, p = 0.007). The presence of comorbidities other than HIV, like diabetes mellitus (p = 0.001), previous pulmonary tuberculosis (p = 0.034) and chronic renal failure (p = 0.007) was associated with hypoalbuminaemia | ||
| 520 | |a CONCLUSION: In this cohort of orthopaedic trauma patients from rural South Africa, we found a 29% prevalence of hypoalbuminaemia at the time of presentation. High-risk subgroups include patients with pre-existing comorbidities and increased age, as well as patients presenting with polytrauma, femoral neck, intertrochanteric femur or tibial plateau fractures | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Albumin | |
| 650 | 4 | |a Global Surgery | |
| 650 | 4 | |a Hypoalbuminaemia | |
| 650 | 4 | |a Orthopaedics | |
| 650 | 4 | |a Rural | |
| 650 | 4 | |a Trauma | |
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| 700 | 1 | |a Maqungo, S |e verfasserin |4 aut | |
| 700 | 1 | |a Marais, L C |e verfasserin |4 aut | |
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