Unexpected diagnosis for a gastric polyp : Granular cell tumor: Case report and review of the literature
Copyright: © Taban et al..
A granular cell tumor (GCT) is a rare neoplasia that originates from Schwann cells. It usually appears in the skin or soft tissues, but it may occur anywhere in the body. The gastrointestinal tract is an unusual developmental site for a GCT, the esophagus being the most common site of origin for this tumor. The stomach is one of the most unique sites of origin for GCT, with less than 80 cases being mentioned in the literature. Histologically, GCTs consist of fusiform and polygonal cells, with granular cytoplasm, arranged in compact 'nests'. Immunohistochemically, these tumors show positivity for S100 protein, CD68, CD56 and, in a smaller percentage, they are positive for other antibodies, most notably inhibin alpha. We report the case of a 52-year-old woman with a solitary GCT that had developed in the gastric cardia, discovered on a routine gastroscopy and successfully treated by endoscopic submucosal dissection.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:21 |
|---|---|
| Enthalten in: |
Experimental and therapeutic medicine - 21(2021), 5 vom: 14. Mai, Seite 536 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Taban, Sorina Maria [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Endoscopic submucosal dissection |
|---|
| Anmerkungen: |
Date Revised 06.04.2021 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.3892/etm.2021.9968 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM323710298 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM323710298 | ||
| 003 | DE-627 | ||
| 005 | 20231225184750.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3892/etm.2021.9968 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1078.xml |
| 035 | |a (DE-627)NLM323710298 | ||
| 035 | |a (NLM)33815609 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Taban, Sorina Maria |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Unexpected diagnosis for a gastric polyp |b Granular cell tumor: Case report and review of the literature |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 06.04.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a Copyright: © Taban et al. | ||
| 520 | |a A granular cell tumor (GCT) is a rare neoplasia that originates from Schwann cells. It usually appears in the skin or soft tissues, but it may occur anywhere in the body. The gastrointestinal tract is an unusual developmental site for a GCT, the esophagus being the most common site of origin for this tumor. The stomach is one of the most unique sites of origin for GCT, with less than 80 cases being mentioned in the literature. Histologically, GCTs consist of fusiform and polygonal cells, with granular cytoplasm, arranged in compact 'nests'. Immunohistochemically, these tumors show positivity for S100 protein, CD68, CD56 and, in a smaller percentage, they are positive for other antibodies, most notably inhibin alpha. We report the case of a 52-year-old woman with a solitary GCT that had developed in the gastric cardia, discovered on a routine gastroscopy and successfully treated by endoscopic submucosal dissection | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a S100 | |
| 650 | 4 | |a endoscopic submucosal dissection | |
| 650 | 4 | |a gastric cardia | |
| 650 | 4 | |a granular cell tumor | |
| 650 | 4 | |a inhibin alpha | |
| 700 | 1 | |a Barna, Robert Alexandru |e verfasserin |4 aut | |
| 700 | 1 | |a Dema, Alis Liliana Carmen |e verfasserin |4 aut | |
| 700 | 1 | |a Ratiu, Iulia Maria |e verfasserin |4 aut | |
| 700 | 1 | |a Popa, Oana |e verfasserin |4 aut | |
| 700 | 1 | |a Plopeanu, Andrei Dorel |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Experimental and therapeutic medicine |d 2010 |g 21(2021), 5 vom: 14. Mai, Seite 536 |w (DE-627)NLM206343205 |x 1792-1015 |7 nnns |
| 773 | 1 | 8 | |g volume:21 |g year:2021 |g number:5 |g day:14 |g month:05 |g pages:536 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.3892/etm.2021.9968 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 21 |j 2021 |e 5 |b 14 |c 05 |h 536 | ||