Laparoscopic versus open resection of intrahepatic cholangiocarcinoma : nationwide analysis
© The Author(s) 2021. Published by Oxford University Press on behalf of BJS Society Ltd. All rights reserved. For permissions, please email: journals.permissionsoup.com..
BACKGROUND: The relevance of laparoscopic resection of intrahepatic cholangiocarcinoma (ICC) remains debated. The aim of this study was to compare laparoscopic (LLR) and open (OLR) liver resection for ICC, with specific focus on textbook outcome and lymph node dissection (LND).
METHODS: Patients undergoing LLR or OLR for ICC were included from two French, nationwide hepatopancreatobiliary surveys undertaken between 2000 and 2017. Patients with negative margins, and without transfusion, severe complications, prolonged hospital stay, readmission or death were considered to have a textbook outcome. Patients who achieved both a textbook outcome and LND were deemed to have an adjusted textbook outcome. OLR and LLR were compared after propensity score matching.
RESULTS: In total, 548 patients with ICC (127 LLR, 421 OLR) were included. Textbook-outcome and LND completion rates were 22.1 and 48.2 per cent respectively. LLR was independently associated with a decreased rate of LND (odds ratio 0.37, 95 per cent c.i. 0.20 to 0.69). After matching, 109 patients remained in each group. LLR was associated with a decreased rate of transfusion (7.3 versus 21.1 per cent; P = 0.001) and shorter hospital stay (median 7 versus 14 days; P = 0.001), but lower rate of LND (33.9 versus 73.4 per cent; P = 0.001). Patients who underwent LLR had lower rate of adjusted TO completion than patients who had OLR (6.5 versus 17.4 per cent; P = 0.012).
CONCLUSION: The laparoscopic approach did not substantially improve quality of care of patients with resectable ICC.
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CommentIn: Br J Surg. 2021 Sep 27;108(9):e311. - PMID 34000027 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:108 |
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| Enthalten in: |
The British journal of surgery - 108(2021), 4 vom: 30. Apr., Seite 419-426 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Hobeika, C [VerfasserIn] |
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Date Completed 10.08.2021 Date Revised 27.09.2021 published: Print CommentIn: Br J Surg. 2021 Sep 27;108(9):e311. - PMID 34000027 Citation Status MEDLINE |
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| doi: |
10.1093/bjs/znaa110 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM323492843 |
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| 100 | 1 | |a Hobeika, C |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Laparoscopic versus open resection of intrahepatic cholangiocarcinoma |b nationwide analysis |
| 264 | 1 | |c 2021 | |
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| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
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| 500 | |a Date Completed 10.08.2021 | ||
| 500 | |a Date Revised 27.09.2021 | ||
| 500 | |a published: Print | ||
| 500 | |a CommentIn: Br J Surg. 2021 Sep 27;108(9):e311. - PMID 34000027 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © The Author(s) 2021. Published by Oxford University Press on behalf of BJS Society Ltd. All rights reserved. For permissions, please email: journals.permissionsoup.com. | ||
| 520 | |a BACKGROUND: The relevance of laparoscopic resection of intrahepatic cholangiocarcinoma (ICC) remains debated. The aim of this study was to compare laparoscopic (LLR) and open (OLR) liver resection for ICC, with specific focus on textbook outcome and lymph node dissection (LND) | ||
| 520 | |a METHODS: Patients undergoing LLR or OLR for ICC were included from two French, nationwide hepatopancreatobiliary surveys undertaken between 2000 and 2017. Patients with negative margins, and without transfusion, severe complications, prolonged hospital stay, readmission or death were considered to have a textbook outcome. Patients who achieved both a textbook outcome and LND were deemed to have an adjusted textbook outcome. OLR and LLR were compared after propensity score matching | ||
| 520 | |a RESULTS: In total, 548 patients with ICC (127 LLR, 421 OLR) were included. Textbook-outcome and LND completion rates were 22.1 and 48.2 per cent respectively. LLR was independently associated with a decreased rate of LND (odds ratio 0.37, 95 per cent c.i. 0.20 to 0.69). After matching, 109 patients remained in each group. LLR was associated with a decreased rate of transfusion (7.3 versus 21.1 per cent; P = 0.001) and shorter hospital stay (median 7 versus 14 days; P = 0.001), but lower rate of LND (33.9 versus 73.4 per cent; P = 0.001). Patients who underwent LLR had lower rate of adjusted TO completion than patients who had OLR (6.5 versus 17.4 per cent; P = 0.012) | ||
| 520 | |a CONCLUSION: The laparoscopic approach did not substantially improve quality of care of patients with resectable ICC | ||
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 700 | 1 | |a Cauchy, F |e verfasserin |4 aut | |
| 700 | 1 | |a Fuks, D |e verfasserin |4 aut | |
| 700 | 1 | |a Barbier, L |e verfasserin |4 aut | |
| 700 | 1 | |a Fabre, J M |e verfasserin |4 aut | |
| 700 | 1 | |a Boleslawski, E |e verfasserin |4 aut | |
| 700 | 1 | |a Regimbeau, J M |e verfasserin |4 aut | |
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| 700 | 1 | |a Cherqui, D |e investigator |4 oth | |
| 700 | 1 | |a Nomi, T |e investigator |4 oth | |
| 700 | 1 | |a Oudafal, N |e investigator |4 oth | |
| 700 | 1 | |a Kawai, T |e investigator |4 oth | |
| 700 | 1 | |a Komatsu, S |e investigator |4 oth | |
| 700 | 1 | |a Okumura, S |e investigator |4 oth | |
| 700 | 1 | |a Petrucciani, N |e investigator |4 oth | |
| 700 | 1 | |a Laurent, A |e investigator |4 oth | |
| 700 | 1 | |a Bucur, P |e investigator |4 oth | |
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| 700 | 1 | |a Sa Cunha, A |e investigator |4 oth | |
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| 700 | 1 | |a Rebibo, L |e investigator |4 oth | |
| 700 | 1 | |a Ferre, L |e investigator |4 oth | |
| 700 | 1 | |a Souche, F R |e investigator |4 oth | |
| 700 | 1 | |a Chauvat, J |e investigator |4 oth | |
| 700 | 1 | |a Jehaes, F |e investigator |4 oth | |
| 700 | 1 | |a Mohkam, K |e investigator |4 oth | |
| 700 | 1 | |a Lesurtel, M |e investigator |4 oth | |
| 700 | 1 | |a Ducerf, C |e investigator |4 oth | |
| 700 | 1 | |a Mabrut, J-Y |e investigator |4 oth | |
| 700 | 1 | |a Hor, T |e investigator |4 oth | |
| 700 | 1 | |a Paye, F |e investigator |4 oth | |
| 700 | 1 | |a Balladur, P |e investigator |4 oth | |
| 700 | 1 | |a Suc, B |e investigator |4 oth | |
| 700 | 1 | |a Muscari, F |e investigator |4 oth | |
| 700 | 1 | |a Millet, G |e investigator |4 oth | |
| 700 | 1 | |a El Amrani, M |e investigator |4 oth | |
| 700 | 1 | |a Ratajczak, C |e investigator |4 oth | |
| 700 | 1 | |a Lecolle, K |e investigator |4 oth | |
| 700 | 1 | |a Truant, S |e investigator |4 oth | |
| 700 | 1 | |a Kianmanesh, A-R |e investigator |4 oth | |
| 700 | 1 | |a Codjia, T |e investigator |4 oth | |
| 700 | 1 | |a Schwarz, L |e investigator |4 oth | |
| 700 | 1 | |a Girard, E |e investigator |4 oth | |
| 700 | 1 | |a Abba, J |e investigator |4 oth | |
| 700 | 1 | |a Letoublon, C |e investigator |4 oth | |
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