Evaluation of Cortactin and HS1 Genes Expression : New Players in Adult B-Cell Acute Lymphoblastic leukemia

OBJECTIVES: This study aimed to assess the prognostic value of cortactin and HS1 genes expression in adult B-cell acute lymphoblastic leukemia.

METHODS: The study included a cohort of 74 adult B-ALL patients and 76 controls. Cortactin and HS1 genes expression were quantified by real time PCR.

RESULTS: The expression of cortactin and HS1 were significantly higher in B-ALL patients at diagnosis as compared to post induction levels (p.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:22

Enthalten in:

Asian Pacific journal of cancer prevention : APJCP - 22(2021), 3 vom: 01. März, Seite 767-774

Sprache:

Englisch

Beteiligte Personen:

Aref, Salah [VerfasserIn]
Al Agdar, Mohamed [VerfasserIn]
Ramez, Ahmed [VerfasserIn]
Abou Zeid, Tarek [VerfasserIn]
Sabry, Mohamed [VerfasserIn]
Khaled, Nada [VerfasserIn]

Links:

Volltext

Themen:

Adaptor Proteins, Signal Transducing
B-ALL, Cortactactin
CTTN protein, human
Cortactin
HCLS1 protein, human
HS1, Prognosis
Journal Article

Anmerkungen:

Date Completed 29.11.2021

Date Revised 29.11.2021

published: Electronic

Citation Status MEDLINE

doi:

10.31557/APJCP.2021.22.3.767

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM323293956