Evaluation of Cortactin and HS1 Genes Expression : New Players in Adult B-Cell Acute Lymphoblastic leukemia
OBJECTIVES: This study aimed to assess the prognostic value of cortactin and HS1 genes expression in adult B-cell acute lymphoblastic leukemia.
METHODS: The study included a cohort of 74 adult B-ALL patients and 76 controls. Cortactin and HS1 genes expression were quantified by real time PCR.
RESULTS: The expression of cortactin and HS1 were significantly higher in B-ALL patients at diagnosis as compared to post induction levels (p.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2021 |
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Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:22 |
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Enthalten in: |
Asian Pacific journal of cancer prevention : APJCP - 22(2021), 3 vom: 01. März, Seite 767-774 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Aref, Salah [VerfasserIn] |
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Links: |
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Themen: |
Adaptor Proteins, Signal Transducing |
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Anmerkungen: |
Date Completed 29.11.2021 Date Revised 29.11.2021 published: Electronic Citation Status MEDLINE |
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doi: |
10.31557/APJCP.2021.22.3.767 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM323293956 |
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500 | |a published: Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a OBJECTIVES: This study aimed to assess the prognostic value of cortactin and HS1 genes expression in adult B-cell acute lymphoblastic leukemia | ||
520 | |a METHODS: The study included a cohort of 74 adult B-ALL patients and 76 controls. Cortactin and HS1 genes expression were quantified by real time PCR | ||
520 | |a RESULTS: The expression of cortactin and HS1 were significantly higher in B-ALL patients at diagnosis as compared to post induction levels (p | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a B-ALL, Cortactactin | |
650 | 4 | |a HS1, Prognosis | |
650 | 7 | |a Adaptor Proteins, Signal Transducing |2 NLM | |
650 | 7 | |a CTTN protein, human |2 NLM | |
650 | 7 | |a Cortactin |2 NLM | |
650 | 7 | |a HCLS1 protein, human |2 NLM | |
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700 | 1 | |a Ramez, Ahmed |e verfasserin |4 aut | |
700 | 1 | |a Abou Zeid, Tarek |e verfasserin |4 aut | |
700 | 1 | |a Sabry, Mohamed |e verfasserin |4 aut | |
700 | 1 | |a Khaled, Nada |e verfasserin |4 aut | |
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