Different-team procurements : A potential solution for the unintended consequences of change in lung allocation policy

© 2021 The American Society of Transplantation and the American Society of Transplant Surgeons..

The new lung allocation policy has led to an increase in distant donors and consequently enhanced logistical burden of procuring organs. Though early single-center studies noted similar outcomes between same-team transplantation (ST, procuring team from transplanting center) and different-team transplantation (DT, procuring team from different center), the efficacy of DT in the contemporary era remains unclear. In this study, we evaluated the trend of DT, rate of transplanting both donor lungs, 1-year graft survival, and risk of Grade 3 primary graft dysfunction (PGD) using the Scientific Registry of Transplant Recipient (SRTR) database from 2006 to 2018. A total of 21619 patients (DT 2085, 9.7%) with 19837 donors were included. Utilization of DT decreased from 15.9% in 2006 to 8.5% in 2018. Proportions of two-lung donors were similar between the groups, and DT had similar 1-year graft survival as ST for both double (DT, HR 1.108, 95% CI 0.894-1.374) and single lung transplants (DT, HR 1.094, 95% CI 0.931-1.286). Risk of Grade 3 PGD was also similar between ST and DT. Given our results, expanding DT may be a feasible option for improving lung procurement efficiency in the current era, particularly in light of the COVID-19 pandemic.

Media Type:

Electronic Article

Year of Publication:

2021

Contained In:

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - Vol. 21, No. 9 (2021), p. 3101-3111

Language:

English

Contributors:

Yang, Zhizhou
Gerull, William D
Shepherd, Hailey M
Marklin, Gary F
Takahashi, Tsuyoshi
Meyers, Bryan F
Kozower, Benjamin D
Patterson, G Alexander
Nava, Ruben G
Hachem, Ramsey R
Witt, Chad A
Byers, Derek E
Vazquez Guillamet, Rodrigo
Pasque, Michael K
Yan, Yan
Kreisel, Daniel
Puri, Varun

Links:

Volltext

Keywords:

*COVID-19
*Lung Transplantation
*Tissue and Organ Procurement
Clinical research / practice
Graft Survival
Humans
Journal Article
Lung
Lung transplantation / pulmonology
Organ procurement and allocation
Pandemics
Policy
Pulmonology, organ procurement
Retrospective Studies
SARS-CoV-2
Scientific Registry for Transplant Recipients (SRTR)
Tissue Donors

Notes:

Date Completed 13.09.2021

Date Revised 13.09.2021

published: Print-Electronic

Citation Status MEDLINE

Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Physical Description:

Online-Ressource

doi:

10.1111/ajt.16553

PMID:

33638937

PPN (Catalogue-ID):

NLM323039391