Is autonomic function during resting-state atypical in Autism : A systematic review of evidence
Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved..
BACKGROUND: Theories of differences in resting-state arousal in autistic individuals are influential. Differences in arousal during resting-state would impact engagement and adaptation to the environment, having a cascading effect on development of attentional and social skills.
OBJECTIVES: We systematically evaluated the evidence for differences in measures of autonomic arousal (heart rate, pupillometry or electrodermal activity) during resting-state in autistic individuals; to understand whether certain contextual or methodological factors impact reports of such differences.
DATA SOURCES: We searched PsycInfo, MEDLINE and EMBASE databases for papers published until 16th May 2019. Of 1207 titles initially identified, 60 met inclusion criteria.
RESULTS AND CONCLUSIONS: Of the 51 studies that investigated group differences between neurotypical and autistic participants, 60.8 % found evidence of group differences. While findings of hyperarousal were more common, particularly using indices of parasympathetic function, findings of hypo-arousal and autonomic dysregulation were also consistently present. Importantly, experimental context played a role in revealing such differences. The evidence is discussed with regard to important methodological factors and implications for future research are described.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:125 |
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| Enthalten in: |
Neuroscience and biobehavioral reviews - 125(2021) vom: 07. Juni, Seite 417-441 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Arora, Iti [VerfasserIn] |
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| Links: |
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| Themen: |
Autism spectrum disorder |
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| Anmerkungen: |
Date Completed 28.06.2021 Date Revised 28.06.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.neubiorev.2021.02.041 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM32219833X |
|---|
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| 100 | 1 | |a Arora, Iti |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Is autonomic function during resting-state atypical in Autism |b A systematic review of evidence |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
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| 500 | |a Date Completed 28.06.2021 | ||
| 500 | |a Date Revised 28.06.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved. | ||
| 520 | |a BACKGROUND: Theories of differences in resting-state arousal in autistic individuals are influential. Differences in arousal during resting-state would impact engagement and adaptation to the environment, having a cascading effect on development of attentional and social skills | ||
| 520 | |a OBJECTIVES: We systematically evaluated the evidence for differences in measures of autonomic arousal (heart rate, pupillometry or electrodermal activity) during resting-state in autistic individuals; to understand whether certain contextual or methodological factors impact reports of such differences | ||
| 520 | |a DATA SOURCES: We searched PsycInfo, MEDLINE and EMBASE databases for papers published until 16th May 2019. Of 1207 titles initially identified, 60 met inclusion criteria | ||
| 520 | |a RESULTS AND CONCLUSIONS: Of the 51 studies that investigated group differences between neurotypical and autistic participants, 60.8 % found evidence of group differences. While findings of hyperarousal were more common, particularly using indices of parasympathetic function, findings of hypo-arousal and autonomic dysregulation were also consistently present. Importantly, experimental context played a role in revealing such differences. The evidence is discussed with regard to important methodological factors and implications for future research are described | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Systematic Review | |
| 650 | 4 | |a Autism spectrum disorder | |
| 650 | 4 | |a Autonomic arousal | |
| 650 | 4 | |a Electrodermal activity | |
| 650 | 4 | |a Heart rate variability | |
| 650 | 4 | |a Pupillometry | |
| 650 | 4 | |a Resting State | |
| 700 | 1 | |a Bellato, Alessio |e verfasserin |4 aut | |
| 700 | 1 | |a Ropar, Danielle |e verfasserin |4 aut | |
| 700 | 1 | |a Hollis, Chris |e verfasserin |4 aut | |
| 700 | 1 | |a Groom, Madeleine J |e verfasserin |4 aut | |
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