Relationship between Bacillus Calmette Guerin Vaccination Policy and Coronavirus Disease-2019 (COVID-19) Incidence

Bacillus Calmette Guerin (BCG) was designed for protecting children against tuberculosis. Also, it can protect against other infectious diseases through the induction of trained immunity. Due to its heterologous protective effects, the BCG vaccine has been proposed as atreatment option for coronavirus disease-2019 (COVID-19). Epidemiological studies have found that countries without BCG vaccination policy have experienced higher mortality rates related toCOVID-19 infection than those with BCG vaccination policy. However, there are some confounding factors such as age, population intensity, immigration, the pandemic phase, and data accuracy that may affect these results. Therefore, this hypothesis should be evaluated by clinical trial studies. Large-scale clinical trials are in progress to investigate ifthe BCG vaccine could be used as a useful tool for protection against COVID-19 infection.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:20

Enthalten in:

Iranian journal of allergy, asthma, and immunology - 20(2021), 1 vom: 11. Feb., Seite 106-113

Sprache:

Englisch

Beteiligte Personen:

Alyasin, Soheila [VerfasserIn]
Kanannejad, Zahra [VerfasserIn]
Esmaeilzadeh, Hossein [VerfasserIn]
Nabavizadeh, Hesamedin [VerfasserIn]
Ghatee, Mohammad Amin [VerfasserIn]
Amin, Reza [VerfasserIn]

Links:

Volltext

Themen:

BCG Vaccine
COVID-19
Journal Article
Mycobacterium bovis

Anmerkungen:

Date Completed 10.03.2021

Date Revised 10.03.2021

published: Electronic

Citation Status MEDLINE

doi:

10.18502/ijaai.v20i1.5417

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM321975316