Platelets as messengers of early-stage cancer
Platelets have an important role in tumor angiogenesis, growth, and metastasis. The reciprocal interaction between cancer and platelets results in changes of several platelet characteristics. It is becoming clear that analysis of these platelet features could offer a new strategy in the search for biomarkers of cancer. Here, we review the human studies in which platelet characteristics (e.g., count, volume, protein, and mRNA content) are investigated in early-stage cancer. The main focus of this paper is to evaluate which platelet features are suitable for the development of a blood test that could detect cancer in its early stages.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:40 |
|---|---|
| Enthalten in: |
Cancer metastasis reviews - 40(2021), 2 vom: 25. Juni, Seite 563-573 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Sabrkhany, Siamack [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Biomarker |
|---|
| Anmerkungen: |
Date Completed 24.08.2021 Date Revised 24.08.2021 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1007/s10555-021-09956-4 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM321924827 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM321924827 | ||
| 003 | DE-627 | ||
| 005 | 20231225180932.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s10555-021-09956-4 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1073.xml |
| 035 | |a (DE-627)NLM321924827 | ||
| 035 | |a (NLM)33634328 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Sabrkhany, Siamack |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Platelets as messengers of early-stage cancer |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 24.08.2021 | ||
| 500 | |a Date Revised 24.08.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Platelets have an important role in tumor angiogenesis, growth, and metastasis. The reciprocal interaction between cancer and platelets results in changes of several platelet characteristics. It is becoming clear that analysis of these platelet features could offer a new strategy in the search for biomarkers of cancer. Here, we review the human studies in which platelet characteristics (e.g., count, volume, protein, and mRNA content) are investigated in early-stage cancer. The main focus of this paper is to evaluate which platelet features are suitable for the development of a blood test that could detect cancer in its early stages | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Biomarker | |
| 650 | 4 | |a Cancer | |
| 650 | 4 | |a Early-stage | |
| 650 | 4 | |a Platelets | |
| 700 | 1 | |a Kuijpers, Marijke J E |e verfasserin |4 aut | |
| 700 | 1 | |a Oude Egbrink, Mirjam G A |e verfasserin |4 aut | |
| 700 | 1 | |a Griffioen, Arjan W |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Cancer metastasis reviews |d 1995 |g 40(2021), 2 vom: 25. Juni, Seite 563-573 |w (DE-627)NLM013060104 |x 1573-7233 |7 nnns |
| 773 | 1 | 8 | |g volume:40 |g year:2021 |g number:2 |g day:25 |g month:06 |g pages:563-573 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s10555-021-09956-4 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 40 |j 2021 |e 2 |b 25 |c 06 |h 563-573 | ||