Video-polysomnographic findings after acute COVID-19 : REM sleep without atonia as sign of CNS pathology?
Copyright © 2021 Elsevier B.V. All rights reserved..
OBJECTIVE: Sleep complaints are frequent after acute COVID-19. Aim of this study was to videopolysomnographically evaluate sleep and sleep disorders after SARS-Cov2 infection.
METHODS: Patients with suspected sleep disorders after acute COVID-19 underwent video-polysomnography (v-PSG) at the Sleep Disorders Clinic, Department of Neurology, Medical University Innsbruck. V-PSG was conducted 4.2 (SD = 1.3) months after diagnosis of SARS-CoV-2 infection.
RESULTS: Eleven patients [nine men, age 52.5 (SD = 11.7) years; BMI 29 (SD = 5.2) kg/m2] were included. At 60 days follow-up after diagnosis, persisting breathing complaints were present in 7/11 (64%) patients. After v-PSG four patients (36%) were diagnosed with obstructive sleep apnea (OSA). Respiratory frequency during sleep was normal and no tachypnea, thoracoabdominal asynchrony, or periodic deep sighing were detected. Four patients (36%) showed REM sleep without atonia (RWA), and two additional patients showed an RWA index within the highest range of normality.
CONCLUSION: We report videopolysomnographic findings in a series of eleven patients after acute COVID-19. A major finding of this study was the presence of isolated RWA, a recognized prodromal stage of RBD, in more than one third of the patients. Future videopolysomnographic investigations including quantification of RWA in patients after COVID-19 will give more insights into a possible acute or post-infectious CNS pathology related to the SARS-CoV-2 infection.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:80 |
|---|---|
| Enthalten in: |
Sleep medicine - 80(2021) vom: 01. Apr., Seite 92-95 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Heidbreder, Anna [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Journal Article |
|---|
| Anmerkungen: |
Date Completed 27.04.2021 Date Revised 21.12.2022 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.sleep.2021.01.051 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM321478509 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM321478509 | ||
| 003 | DE-627 | ||
| 005 | 20231225175906.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.sleep.2021.01.051 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1071.xml |
| 035 | |a (DE-627)NLM321478509 | ||
| 035 | |a (NLM)33588262 | ||
| 035 | |a (PII)S1389-9457(21)00068-X | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Heidbreder, Anna |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Video-polysomnographic findings after acute COVID-19 |b REM sleep without atonia as sign of CNS pathology? |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 27.04.2021 | ||
| 500 | |a Date Revised 21.12.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2021 Elsevier B.V. All rights reserved. | ||
| 520 | |a OBJECTIVE: Sleep complaints are frequent after acute COVID-19. Aim of this study was to videopolysomnographically evaluate sleep and sleep disorders after SARS-Cov2 infection | ||
| 520 | |a METHODS: Patients with suspected sleep disorders after acute COVID-19 underwent video-polysomnography (v-PSG) at the Sleep Disorders Clinic, Department of Neurology, Medical University Innsbruck. V-PSG was conducted 4.2 (SD = 1.3) months after diagnosis of SARS-CoV-2 infection | ||
| 520 | |a RESULTS: Eleven patients [nine men, age 52.5 (SD = 11.7) years; BMI 29 (SD = 5.2) kg/m2] were included. At 60 days follow-up after diagnosis, persisting breathing complaints were present in 7/11 (64%) patients. After v-PSG four patients (36%) were diagnosed with obstructive sleep apnea (OSA). Respiratory frequency during sleep was normal and no tachypnea, thoracoabdominal asynchrony, or periodic deep sighing were detected. Four patients (36%) showed REM sleep without atonia (RWA), and two additional patients showed an RWA index within the highest range of normality | ||
| 520 | |a CONCLUSION: We report videopolysomnographic findings in a series of eleven patients after acute COVID-19. A major finding of this study was the presence of isolated RWA, a recognized prodromal stage of RBD, in more than one third of the patients. Future videopolysomnographic investigations including quantification of RWA in patients after COVID-19 will give more insights into a possible acute or post-infectious CNS pathology related to the SARS-CoV-2 infection | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Neurodegeneration | |
| 650 | 4 | |a Polysomnography | |
| 650 | 4 | |a REM sleep without atonia | |
| 650 | 4 | |a SARS-Cov2 | |
| 650 | 4 | |a Sleep apnea | |
| 700 | 1 | |a Sonnweber, Thomas |e verfasserin |4 aut | |
| 700 | 1 | |a Stefani, Ambra |e verfasserin |4 aut | |
| 700 | 1 | |a Ibrahim, Abubaker |e verfasserin |4 aut | |
| 700 | 1 | |a Cesari, Matteo |e verfasserin |4 aut | |
| 700 | 1 | |a Bergmann, Melanie |e verfasserin |4 aut | |
| 700 | 1 | |a Brandauer, Elisabeth |e verfasserin |4 aut | |
| 700 | 1 | |a Tancevski, Ivan |e verfasserin |4 aut | |
| 700 | 1 | |a Löffler-Ragg, Judith |e verfasserin |4 aut | |
| 700 | 1 | |a Högl, Birgit |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Sleep medicine |d 2000 |g 80(2021) vom: 01. Apr., Seite 92-95 |w (DE-627)NLM106609017 |x 1878-5506 |7 nnns |
| 773 | 1 | 8 | |g volume:80 |g year:2021 |g day:01 |g month:04 |g pages:92-95 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.sleep.2021.01.051 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 80 |j 2021 |b 01 |c 04 |h 92-95 | ||