Myelin development in visual scene-network tracts beyond late childhood : A multimethod neuroimaging study
Copyright © 2021 Elsevier Ltd. All rights reserved..
The visual scene-network-comprising the parahippocampal place area (PPA), retrosplenial cortex (RSC), and occipital place area (OPA)-shows a prolonged functional development. Structural development of white matter that underlies the scene-network has not been investigated despite its potential influence on scene-network function. The key factor for white matter maturation is myelination. However, research on myelination using the gold standard method of post-mortem histology is scarce. In vivo alternatives diffusion-weighted imaging (DWI) and myelin water imaging (MWI) so far report broad-scale findings that prohibit inferences concerning the scene-network. Here, we combine MWI, DWI tractography, and fMRI to investigate myelination in scene-network tracts in middle childhood, late childhood, and adulthood. We report increasing myelin from middle childhood to adulthood in right PPA-OPA, and trends towards increases in the left and right RSC-OPA tracts. Investigating tracts to regions highly connected with the scene-network, such as early visual cortex and the hippocampus, did not yield any significant age group differences. Our findings indicate that structural development coincides with functional development in the scene-network, possibly enabling structure-function interactions.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:137 |
|---|---|
| Enthalten in: |
Cortex; a journal devoted to the study of the nervous system and behavior - 137(2021) vom: 15. Apr., Seite 18-34 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Meissner, Tobias W [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Connectivity |
|---|
| Anmerkungen: |
Date Completed 07.07.2021 Date Revised 07.07.2021 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.cortex.2020.12.016 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM321477200 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM321477200 | ||
| 003 | DE-627 | ||
| 005 | 20231225175904.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.cortex.2020.12.016 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1071.xml |
| 035 | |a (DE-627)NLM321477200 | ||
| 035 | |a (NLM)33588130 | ||
| 035 | |a (PII)S0010-9452(21)00003-4 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Meissner, Tobias W |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Myelin development in visual scene-network tracts beyond late childhood |b A multimethod neuroimaging study |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 07.07.2021 | ||
| 500 | |a Date Revised 07.07.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2021 Elsevier Ltd. All rights reserved. | ||
| 520 | |a The visual scene-network-comprising the parahippocampal place area (PPA), retrosplenial cortex (RSC), and occipital place area (OPA)-shows a prolonged functional development. Structural development of white matter that underlies the scene-network has not been investigated despite its potential influence on scene-network function. The key factor for white matter maturation is myelination. However, research on myelination using the gold standard method of post-mortem histology is scarce. In vivo alternatives diffusion-weighted imaging (DWI) and myelin water imaging (MWI) so far report broad-scale findings that prohibit inferences concerning the scene-network. Here, we combine MWI, DWI tractography, and fMRI to investigate myelination in scene-network tracts in middle childhood, late childhood, and adulthood. We report increasing myelin from middle childhood to adulthood in right PPA-OPA, and trends towards increases in the left and right RSC-OPA tracts. Investigating tracts to regions highly connected with the scene-network, such as early visual cortex and the hippocampus, did not yield any significant age group differences. Our findings indicate that structural development coincides with functional development in the scene-network, possibly enabling structure-function interactions | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Connectivity | |
| 650 | 4 | |a Diffusion weighted imaging | |
| 650 | 4 | |a Maturation | |
| 650 | 4 | |a Scene recognition | |
| 650 | 4 | |a White matter | |
| 700 | 1 | |a Genç, Erhan |e verfasserin |4 aut | |
| 700 | 1 | |a Mädler, Burkhard |e verfasserin |4 aut | |
| 700 | 1 | |a Weigelt, Sarah |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Cortex; a journal devoted to the study of the nervous system and behavior |d 1969 |g 137(2021) vom: 15. Apr., Seite 18-34 |w (DE-627)NLM000759058 |x 1973-8102 |7 nnns |
| 773 | 1 | 8 | |g volume:137 |g year:2021 |g day:15 |g month:04 |g pages:18-34 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.cortex.2020.12.016 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 137 |j 2021 |b 15 |c 04 |h 18-34 | ||