Association of Protein Intake during the Second Year of Life with Weight Gain-Related Outcomes in Childhood : A Systematic Review

There is accumulating evidence that early protein intake is related with weight gain in childhood. However, the evidence is mostly limited to the first year of life, whereas the high-weight-gain-velocity period extends up to about 2 years of age. We aimed to investigate whether protein intake during the second year of life is associated with higher weight gain and obesity risk later in childhood. We conducted a systematic review with searches in both PubMed®/MEDLINE® and the Cochrane Central Register of Controlled Trials. Ten studies that assessed a total of 46,170 children were identified. We found moderate-quality evidence of an association of protein intake during the second year of life with fat mass at 2 years and at 7 years. Effects on other outcomes such as body mass index (BMI), obesity risk, or adiposity rebound onset were inconclusive due to both heterogeneity and low evidence. We conclude that higher protein intakes during the second year of life are likely to increase fatness in childhood, but there is limited evidence regarding the association with other outcomes such as body mass index or change in adiposity rebound onset. Further well-designed and adequately powered clinical trials are needed since this issue has considerable public health relevance.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:13

Enthalten in:

Nutrients - 13(2021), 2 vom: 10. Feb.

Sprache:

Englisch

Beteiligte Personen:

Ferré, Natalia [VerfasserIn]
Luque, Verónica [VerfasserIn]
Closa-Monasterolo, Ricardo [VerfasserIn]
Zaragoza-Jordana, Marta [VerfasserIn]
Gispert-Llauradó, Mariona [VerfasserIn]
Grote, Veit [VerfasserIn]
Koletzko, Berthold [VerfasserIn]
Escribano, Joaquín [VerfasserIn]

Links:

Volltext

Themen:

Dietary Proteins
Early protein intake
Journal Article
Metabolic programming
Obesity risk
Systematic Review
Systematic review

Anmerkungen:

Date Completed 04.05.2021

Date Revised 19.09.2023

published: Electronic

Citation Status MEDLINE

doi:

10.3390/nu13020583

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM321384954