An early experience of COVID-19 disease in pediatric and young adult renal transplant recipients
© 2021 Wiley Periodicals LLC..
BACKGROUND: COVID-19 is caused by a novel form of coronavirus known as SARS-CoV-2. Patients can present with a wide variety of symptoms from fever to severe respiratory distress. Immunocompromised patients, including solid organ transplant recipients, may present with atypical symptoms, making the diagnosis of COVID-19 more difficult to make. New reports have been emerging about the management of COVID-19 disease in adult renal transplant recipients. However, very little is known in pediatric renal transplant recipients.
METHODS: Here, we describe a case report of four pediatric renal transplant recipients who presented with mild-to-moderate COVID-19 disease.
RESULTS: All patients presented with upper respiratory infection symptoms, with one requiring hospitalization for hypoxia. Patients were treated mostly with supportive care. Two of the patients developed AKI which resolved four to eight weeks after illness. All four patients developed COVID IgG antibodies one to two months after becoming infected.
CONCLUSION: This case series demonstrates that immunocompromised renal transplant recipients have comparable outcomes compared with immunocompetent children.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:25 |
|---|---|
| Enthalten in: |
Pediatric transplantation - 25(2021), 5 vom: 17. Aug., Seite e13972 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Solomon, Sonia [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
COVID-19 |
|---|
| Anmerkungen: |
Date Completed 09.08.2021 Date Revised 27.07.2022 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1111/petr.13972 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM320638790 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM320638790 | ||
| 003 | DE-627 | ||
| 005 | 20231225174016.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1111/petr.13972 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1068.xml |
| 035 | |a (DE-627)NLM320638790 | ||
| 035 | |a (NLM)33502074 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Solomon, Sonia |e verfasserin |4 aut | |
| 245 | 1 | 3 | |a An early experience of COVID-19 disease in pediatric and young adult renal transplant recipients |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 09.08.2021 | ||
| 500 | |a Date Revised 27.07.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2021 Wiley Periodicals LLC. | ||
| 520 | |a BACKGROUND: COVID-19 is caused by a novel form of coronavirus known as SARS-CoV-2. Patients can present with a wide variety of symptoms from fever to severe respiratory distress. Immunocompromised patients, including solid organ transplant recipients, may present with atypical symptoms, making the diagnosis of COVID-19 more difficult to make. New reports have been emerging about the management of COVID-19 disease in adult renal transplant recipients. However, very little is known in pediatric renal transplant recipients | ||
| 520 | |a METHODS: Here, we describe a case report of four pediatric renal transplant recipients who presented with mild-to-moderate COVID-19 disease | ||
| 520 | |a RESULTS: All patients presented with upper respiratory infection symptoms, with one requiring hospitalization for hypoxia. Patients were treated mostly with supportive care. Two of the patients developed AKI which resolved four to eight weeks after illness. All four patients developed COVID IgG antibodies one to two months after becoming infected | ||
| 520 | |a CONCLUSION: This case series demonstrates that immunocompromised renal transplant recipients have comparable outcomes compared with immunocompetent children | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a pediatrics | |
| 650 | 4 | |a renal transplant | |
| 650 | 7 | |a Immunoglobulin G |2 NLM | |
| 700 | 1 | |a Pereira, Tanya |e verfasserin |4 aut | |
| 700 | 1 | |a Samsonov, Dmitry |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Pediatric transplantation |d 1997 |g 25(2021), 5 vom: 17. Aug., Seite e13972 |w (DE-627)NLM097406473 |x 1399-3046 |7 nnns |
| 773 | 1 | 8 | |g volume:25 |g year:2021 |g number:5 |g day:17 |g month:08 |g pages:e13972 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1111/petr.13972 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 25 |j 2021 |e 5 |b 17 |c 08 |h e13972 | ||