A Fluorescent Visual Proton Donor and Photoacid Sterilant Based on Sulfonate-conjugated BODIPY

Increasing acidity is an effective method for bacterial inactivation by inhibiting the synthesis of intracellular proteins at low pH. Photo-driven proton release probe can be used for the measurement of proton in hydrophobic condition. To develop fluorescent proton donor, two boron dipyrromethene derivatives (BDP-S and BDP-S2) were characterized by spectroscopic methods. Irradiation of BDP-S by white LED light resulted in efficient generation of acidic species with changes of fluorescence emission. The linear relationship between the pH value and the fluorescence intensity of BDP-S was obtained, indicating that BDP-S is a fluorescent visual proton donor. Light-induced antibacterial results indicate that BDP-S can significantly inhibit the growth of E. coli. The results prove that BDP-S is a very promising photoacid sterilant.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:31

Enthalten in:

Journal of fluorescence - 31(2021), 2 vom: 15. März, Seite 501-507

Sprache:

Englisch

Beteiligte Personen:

Ali, Abbas Mohammed [VerfasserIn]
Shao, Jian [VerfasserIn]
Wang, Jia-Xin [VerfasserIn]
Chen, Qiu-Yun [VerfasserIn]
Li, Yang [VerfasserIn]
Qu, Ling-Ling [VerfasserIn]

Links:

Volltext

Themen:

4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
Anti-Bacterial Agents
Antibacterial
BODIPY
Boron Compounds
Fluorescent Dyes
Journal Article
Photoacid generator
Proton donor
Protons
Sulfonic Acids

Anmerkungen:

Date Completed 05.10.2021

Date Revised 05.10.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s10895-021-02682-8

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM320124509