A Fluorescent Visual Proton Donor and Photoacid Sterilant Based on Sulfonate-conjugated BODIPY
Increasing acidity is an effective method for bacterial inactivation by inhibiting the synthesis of intracellular proteins at low pH. Photo-driven proton release probe can be used for the measurement of proton in hydrophobic condition. To develop fluorescent proton donor, two boron dipyrromethene derivatives (BDP-S and BDP-S2) were characterized by spectroscopic methods. Irradiation of BDP-S by white LED light resulted in efficient generation of acidic species with changes of fluorescence emission. The linear relationship between the pH value and the fluorescence intensity of BDP-S was obtained, indicating that BDP-S is a fluorescent visual proton donor. Light-induced antibacterial results indicate that BDP-S can significantly inhibit the growth of E. coli. The results prove that BDP-S is a very promising photoacid sterilant.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2021 |
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Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:31 |
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Enthalten in: |
Journal of fluorescence - 31(2021), 2 vom: 15. März, Seite 501-507 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Ali, Abbas Mohammed [VerfasserIn] |
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Links: |
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Themen: |
4,4-difluoro-4-bora-3a,4a-diaza-s-indacene |
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Anmerkungen: |
Date Completed 05.10.2021 Date Revised 05.10.2021 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1007/s10895-021-02682-8 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM320124509 |
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520 | |a Increasing acidity is an effective method for bacterial inactivation by inhibiting the synthesis of intracellular proteins at low pH. Photo-driven proton release probe can be used for the measurement of proton in hydrophobic condition. To develop fluorescent proton donor, two boron dipyrromethene derivatives (BDP-S and BDP-S2) were characterized by spectroscopic methods. Irradiation of BDP-S by white LED light resulted in efficient generation of acidic species with changes of fluorescence emission. The linear relationship between the pH value and the fluorescence intensity of BDP-S was obtained, indicating that BDP-S is a fluorescent visual proton donor. Light-induced antibacterial results indicate that BDP-S can significantly inhibit the growth of E. coli. The results prove that BDP-S is a very promising photoacid sterilant | ||
650 | 4 | |a Journal Article | |
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650 | 7 | |a Sulfonic Acids |2 NLM | |
700 | 1 | |a Shao, Jian |e verfasserin |4 aut | |
700 | 1 | |a Wang, Jia-Xin |e verfasserin |4 aut | |
700 | 1 | |a Chen, Qiu-Yun |e verfasserin |4 aut | |
700 | 1 | |a Li, Yang |e verfasserin |4 aut | |
700 | 1 | |a Qu, Ling-Ling |e verfasserin |4 aut | |
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