Inflammation to Infertility : Panoramic View on Endometriosis

Copyright © 2020, Mohammed Rasheed et al..

Endometriosis is a disease caused by the implantation of endometrial glands and stroma outside the uterine cavity. It affects 10% of the reproductive-age women this means that 190 million women are affected worldwide. The definitive diagnosis requires surgical exploration or a laparoscopy which is of a high expense. The pathogenesis of the disease is heterogeneous and poorly understood despite the progress in the research field. Infertility is one of the main symptoms of Endometriosis. The mechanism behind this remains unclear. Literature suggests that Endometriosis reduces implantation capacity, increases the risk of pregnancy loss, and causes anatomical obstruction imposed by endometriotic lesions. The disease has a high burden to it by decreasing the quality of women's life and imposing negative consequences for their productivity, social life, and emotional wellbeing. Since inflammation is considered the hallmark of endometriosis, it is worth looking at the mechanism of how inflammation is linked to infertility in endometriosis patients. In this study, we summarized the recent finding of how inflammation can affect oocyte, endometrium, hormones, and sperm.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:12

Enthalten in:

Cureus - 12(2020), 11 vom: 16. Nov., Seite e11516

Sprache:

Englisch

Beteiligte Personen:

Mohammed Rasheed, Huda A [VerfasserIn]
Hamid, Pousette [VerfasserIn]

Links:

Volltext

Themen:

Endometriosis
Infertility
Inflammation and infertility
Journal Article
Review

Anmerkungen:

Date Revised 10.11.2023

published: Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.7759/cureus.11516

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM319189058