OCTA-guided navigated laser therapy for advanced macula neovascularization secondary to age related macular degeneration
INTRODUCTION: To evaluate the effects of the Navilas system guided by optical coherence tomography angiography for advanced macular neovascularization (MNV) secondary to age-related macular degeneration (AMD).
METHODS: Prospective case-series including nine eyes presenting with advanced MNV with persistence of exudative signs, no longer responding to anti-VEGF therapy, best-corrected visual acuity at least of 1.3 logMar. All patients were treated with Navilas guided by overlaid optical coherence tomography angiography (OCTA) images at the site of branching large neovascular trunks.
RESULTS: Occlusion of large neovascular trunks successfully occurred in all nine included patients. OCTA analysis revealed, at 1 month follow up, MNV total area decreasing from 6.2 ± 3.1 to 2.6 ± 3.4 mm2. At 6 months follow up, mean MNV area was 3.3 ± 3.4 mm2 (p = 0.008).
CONCLUSION: This preliminary study showed that Navilas treatment guided by OCTA may represent an attractive therapeutic option in advanced neovascular lesions secondary to AMD.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:31 |
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| Enthalten in: |
European journal of ophthalmology - 31(2021), 6 vom: 01. Nov., Seite 3182-3189 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Amoroso, Francesca [VerfasserIn] |
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| Links: |
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| Themen: |
Age-related macular degeneration |
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| Anmerkungen: |
Date Completed 23.11.2021 Date Revised 28.04.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1177/1120672120983191 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM319179192 |
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| 100 | 1 | |a Amoroso, Francesca |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a OCTA-guided navigated laser therapy for advanced macula neovascularization secondary to age related macular degeneration |
| 264 | 1 | |c 2021 | |
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| 500 | |a Date Completed 23.11.2021 | ||
| 500 | |a Date Revised 28.04.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a INTRODUCTION: To evaluate the effects of the Navilas system guided by optical coherence tomography angiography for advanced macular neovascularization (MNV) secondary to age-related macular degeneration (AMD) | ||
| 520 | |a METHODS: Prospective case-series including nine eyes presenting with advanced MNV with persistence of exudative signs, no longer responding to anti-VEGF therapy, best-corrected visual acuity at least of 1.3 logMar. All patients were treated with Navilas guided by overlaid optical coherence tomography angiography (OCTA) images at the site of branching large neovascular trunks | ||
| 520 | |a RESULTS: Occlusion of large neovascular trunks successfully occurred in all nine included patients. OCTA analysis revealed, at 1 month follow up, MNV total area decreasing from 6.2 ± 3.1 to 2.6 ± 3.4 mm2. At 6 months follow up, mean MNV area was 3.3 ± 3.4 mm2 (p = 0.008) | ||
| 520 | |a CONCLUSION: This preliminary study showed that Navilas treatment guided by OCTA may represent an attractive therapeutic option in advanced neovascular lesions secondary to AMD | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Age-related macular degeneration | |
| 650 | 4 | |a RETINA | |
| 650 | 4 | |a retina - medical therapies | |
| 650 | 4 | |a retinal pathology/research | |
| 650 | 4 | |a techniques of retinal examination | |
| 650 | 7 | |a Angiogenesis Inhibitors |2 NLM | |
| 700 | 1 | |a Souied, Eric H |e verfasserin |4 aut | |
| 700 | 1 | |a Cohen, Salomon Yves |e verfasserin |4 aut | |
| 700 | 1 | |a Pedinielli, Alexandre |e verfasserin |4 aut | |
| 700 | 1 | |a Astroz, Polina |e verfasserin |4 aut | |
| 700 | 1 | |a Blanco Garavito, Rocio |e verfasserin |4 aut | |
| 700 | 1 | |a Capuano, Vittorio |e verfasserin |4 aut | |
| 700 | 1 | |a Querques, Giuseppe |e verfasserin |4 aut | |
| 700 | 1 | |a Miere, Alexandra |e verfasserin |4 aut | |
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