Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances

Development trends need the necessity for wider use of the local resources and available natural materials are one of the priorities around the world. Freshwater sapropel is a common material in the water basement of the lakes, but still not sufficiently explored. The main goal of the project to start detailed and systematic research on the medical properties of sapropel to be obtained in Latvia, promote its scientifically based use in balneology, develop new medical procedures and services, and promote development of new exportable products. The results include the survey, sampling depths, and processing, evaluation of external signs, physical, chemical, and biochemical parameters, and evaluation of microbiological indicators. Active components from the sapropel samples extracted using the alkaline method. Sapropel extracts were characterized by organic carbon content, humic and fulvic acid concentrations, total phenolic content, trace metal and pesticide concentrations, total antioxidant status, and microbiological flora. Summarizing the article's main findings it was concluded that Latvian freshwater sapropel can be used as raw material for obtaining sapropel extract and use it in the preparation of pharmaceuticals and promote the development of new exportable products and services.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:10

Enthalten in:

Scientific reports - 10(2020), 1 vom: 09. Dez., Seite 21527

Sprache:

Englisch

Beteiligte Personen:

Pavlovska, Ilona [VerfasserIn]
Klavina, Aneka [VerfasserIn]
Auce, Agris [VerfasserIn]
Vanadzins, Ivars [VerfasserIn]
Silova, Alise [VerfasserIn]
Komarovska, Laura [VerfasserIn]
Silamikele, Baiba [VerfasserIn]
Dobkevica, Linda [VerfasserIn]
Paegle, Linda [VerfasserIn]

Links:

Volltext

Themen:

64083-34-7
Benzopyrans
Fulvic acid
Humic Substances
Journal Article
Pharmaceutical Preparations
Research Support, Non-U.S. Gov't
Sapropel
Soil
Trace Elements
XII14C5FXV

Anmerkungen:

Date Completed 04.05.2021

Date Revised 04.05.2021

published: Electronic

Citation Status MEDLINE

doi:

10.1038/s41598-020-78498-6

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM318644568