Osseous Metaplasia in Low-grade Ovarian Serous Carcinoma With a BRAF Mutation : A Case Report
Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc.on behalf of the International Society of Gynecological Pathologists..
A 44-yr-old woman presented with lower, painless abdominal discomfort and a vacuolated mass measuring 12 cm on the right-hand side of the pelvis. She subsequently underwent a bilateral salpingo-oophorectomy. An osseous lesion was identified in the left ovary, which was hard in consistency and was associated with a multicystic complex lesion. Microscopic examination of the left ovary showed clusters of serous cells with moderate atypia, surrounded by a desmoplastic stroma with large areas of bone matrix. To the best of our knowledge, this is the first reported case of low-grade serous carcinoma with osseous metaplasia and a BRAF mutation.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:40 |
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| Enthalten in: |
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 40(2021), 5 vom: 01. Sept., Seite 448-451 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Catteau, Xavier [VerfasserIn] |
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| Links: |
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| Themen: |
BRAF protein, human |
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| Anmerkungen: |
Date Completed 20.12.2021 Date Revised 23.08.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.1097/PGP.0000000000000732 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM318187892 |
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| 520 | |a Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc.on behalf of the International Society of Gynecological Pathologists. | ||
| 520 | |a A 44-yr-old woman presented with lower, painless abdominal discomfort and a vacuolated mass measuring 12 cm on the right-hand side of the pelvis. She subsequently underwent a bilateral salpingo-oophorectomy. An osseous lesion was identified in the left ovary, which was hard in consistency and was associated with a multicystic complex lesion. Microscopic examination of the left ovary showed clusters of serous cells with moderate atypia, surrounded by a desmoplastic stroma with large areas of bone matrix. To the best of our knowledge, this is the first reported case of low-grade serous carcinoma with osseous metaplasia and a BRAF mutation | ||
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